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Poppi Trial Recruits its First Infant

Poppi, a trial looking at whether morphine is an effective analgesic for procedural pain in infants, recruited its first infant this week. Thank you to the family who agreed to take part.

Poppi trial has launched

The Poppi Trial has been designed to test whether morphine can provide effective pain relief in babies during invasive medical procedures.

Led by Dr Eleri Adams and Dr Rebeccah Slater in collaboration with the NPEU and the Paediatric and Infant Pain & Anaesthesia (PiPA) group, the trial is due to recruit the first patient at the John Radcliffe Hospital in Oxford next week.

University of Oxford publishes article on the PiPA Group's work

The University of Oxford have published an article about the PiPA Group's work investigating how babies respond to pain.

Read the full article.

New research on pain relief in babies starting soon

Infant pain has both immediate and long-term negative consequences, yet in clinical practice it is often under-treated and very few pain-relieving drugs have been tested in babies. The Poppi Trial has been designed to test whether morphine can provide effective pain relief in babies during invasive medical procedures. Led by Dr Rebeccah Slater in collaboration with the NPEU and the Paediatric and Infant Pain & Anaesthesia (PiPA) group, the trial is due to start recruitment at the John Radcliffe Hospital in Oxford in Spring 2016. Read the summary protocol published in the Lancet for more information. 

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The Poppi trial is funded by The Wellcome Trust and the NIHR EME Programme.

NIHR acknowledgment and disclaimer: This study is funded by the National Institute for Health Research (NIHR) Efficacy and Mechanism Evaluation (EME) Programme (Reference Number 14/187/01). The views expressed are those of the author(s) and not necessarily those of the NIHR or the Department of Health and Social Care.