Important Notice

In light of the COVID-19 outbreak, recruitment to NeoCLEAR was paused on 18th March 2020. Recruitment has since restarted at the John Radcliffe Hospital, Southmead Hospital, Medway Maritime Hospital, Northampton General Hospital, Leicester Royal Infirmary and Norfolk & Norwich University Hospital.

NeoCLEAR: Neonatal Champagne Lumbar punctures Every time – An RCT is a multicentre, randomised controlled trial to investigate techniques to increase lumbar puncture success in newborn babies. Lumbar puncture is a procedure performed to diagnose meningitis or another neurological condition, and sometimes as treatment for certain neurological problems. The main aim of the NeoCLEAR trial is to understand if there is a best technique for achieving a successful lumbar puncture in newborn babies, 'best' being defined as the technique which produces the clearest sample of cerebrospinal fluid (CSF) in the fewest possible number of attempts.

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