NeoCLEAR: Neonatal Champagne Lumbar punctures Every time – An RCT is a multicentre, randomised controlled trial to investigate techniques to increase lumbar puncture success in newborn babies. Lumbar puncture is a procedure performed to diagnose meningitis or another neurological condition, and sometimes as treatment for certain neurological problems. The main aim of the NeoCLEAR trial is to understand if there is a best technique for achieving a successful lumbar puncture in newborn babies, ‘best’ being defined as the technique which produces the clearest sample of cerebrospinal fluid (CSF) in the fewest possible number of attempts.
If one of the four combinations of techniques is found to be more effective than others, the hope is that the results of this study will help inform the care of babies in the future.
- REC Reference:
- Clinical Trials Unit:
- National Perinatal Epidemiology Unit CTU
- University of Oxford
- NIHR Health Technology Assessment (HTA) Programme
- Recruitment Target:
- Duration of Study:
- September 2017 - August 2020