NeoCLEAR

NeoCLEAR: Neonatal Champagne Lumbar punctures Every time – An RCT is a multicentre, randomised controlled trial to investigate techniques to increase lumbar puncture success in newborn babies. Lumbar puncture is a procedure performed to diagnose meningitis or another neurological condition, and sometimes as treatment for certain neurological problems. The main aim of the NeoCLEAR trial is to understand if there is a best technique for achieving a successful lumbar puncture in newborn babies, ‘best’ being defined as the technique which produces the clearest sample of cerebrospinal fluid (CSF) in the fewest possible number of attempts.

Recruitment
Total
0116
Target
1020

The latest infant was recruited at John Radcliffe Hospital, Oxford on 13 December 2018

If one of the four combinations of techniques is found to be more effective than others, the hope is that the results of this study will help inform the care of babies in the future.

EudraCT No.:
N/A
REC Reference:
18/SC/0222
ISRCTN:
14040914
Clinical Trials Unit:
National Perinatal Epidemiology Unit CTU
Sponsor:
University of Oxford
Funder:
NIHR Health Technology Assessment (HTA) Programme
Recruitment Target:
1,020
Duration of Study:
September 2017 - August 2020