Trials Portfolio
Trials in Set-up
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Developmental Outcome of Long-Term Feed Supplementation in Neonates: does nutritional supplementation improve cognitive outcomes for preterms and infants with hypoxic ischaemic encephalopathy?
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Positive End-Expiratory Pressure (PEEP) Levels during Resuscitation of Preterm Infants at Birth: Does a high, dynamic PEEP strategy to support the lung improve outcomes in extremely preterm infants?
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Treating Oesophageal Atresia to prevent Stricture: A multicentre, randomised trial of gastric acid suppression medication for treating oesophageal atresia to prevent stricture.
Recruiting Trials
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EXpressing in PREmaturity – Simple interventionS: Does a guided relaxation audio track increase yield of expressed milk in mothers of very preterm infants?
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SURFactant Or Not: randomised controlled trial of early surfactant therapy versus expectant management in late preterm and early term infants with respiratory distress.
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Timing of Stoma Closure in Neonates: A study to assess feasibility of performing a randomised controlled trial comparing early and late stoma closure in neonates.
Analysis & Dissemination
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Antiseptic Randomised Controlled Trial for Insertion of Catheters: comparing two topical antiseptic solutions used prior to percutaneous central venous catheter insertion in preterm neonates.
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Freezing of embryos in assisted conception: evaluating clinical and cost-effectiveness of freezing embryos followed by thawed frozen embryo transfer, compared with fresh embryo transfer, in women undergoing IVF.
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A randomised controlled trial of FRenotomy and breastfeeding support Or breastfeeding Support without frenotomy to investigate continuation of breastfeeding for babies with Tongue-TIE.
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NeoCLEAR: Neonatal Champagne Lumbar punctures Every time - An RCT. A multicentre, randomised controlled 2x2 factorial trial to investigate techniques to increase lumbar puncture success.
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Pre-eclampsia in HOspital: Early iNductIon or eXpectant management: Does delivery in women with pre-eclampsia at 34 to 36 weeks gestation reduce maternal complications compared to expectant management?
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WithHolding Enteral feeds Around packed red cell Transfusion to prevent necrotising enterocolitis in preterm neonates: A multi-centre, electronic patient record, randomised controlled pilot trial.