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Baby Oscar Trial results published

Early treatment of patent ductus arteriosus with ibuprofen does not help to improve short-term outcomes for preterm babies

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Baby-OSCAR is a multi-centre randomised controlled trial, co-ordinated from the National Perinatal Epidemiology Unit Clinical Trial unit (NPEU CTU) at the University of Oxford and aiming to find out whether or not a confirmed large Patent Ductus Arteriosus (PDA) in very premature babies should be treated with ibuprofen within 72 hours of birth. Funding is provided by the National Institute of Health Research (NIHR) Health Technology Assessment (HTA) programme (project reference 11/92/15) and sponsored by the University of Oxford.

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Recruitment total: 653
Recruitment to the Baby-OSCAR trial is now closed. We would like to thank all the families and site staff who took part.