NeoCLEAR

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NeoCLEAR: Neonatal Champagne Lumbar punctures Every time - An RCT. A multicentre, randomised controlled 2x2 factorial trial to investigate techniques to increase lumbar puncture success

Trial started: 2017 Trial ended: 2020

Show Publications

Roehr CC, Marshall ASJ, Scrivens A, Sadarangani M, Williams R, Yong J, et al. Techniques to increase lumbar puncture success in newborn babies: the NeoCLEAR RCT. Health Technol Assess 2023;27(33).
https://doi.org/10.3310/THJY0671
Marshall ASJ, Scrivens A, Bell JL, Linsell L, Hardy P, Yong J, et al. Assessment of infant position and timing of stylet removal to improve lumbar puncture success in neonates (NeoCLEAR): an open-label, 2 x 2 factorial, randomised, controlled trial. Lancet Child Adolesc Health. 2023;7(2):91-100
http://doi.org/10.1016/s2352-4642(22)00343-1
Marshall A, Sadarangani M, Scrivens A, Williams R, Yong J, Bowler U, et al. Champagne and bloody taps: can we improve the success rate of neonatal lumbar punctures? Infant. 2018;14(6):224-26
https://www.abacusdx.com/media/NeoCLEAR.PDF

Published Protocol

Marshall ASJ, Sadarangani M, Scrivens A, Williams R, Yong J, Bowler U, Linsell L, Chiocchia V, Bell JL, Stokes C, Santhanadass P, Adams E, Juszczak E, Roehr CC, on behalf of the The Neo Clear Collaborative Group. Study protocol: NeoCLEAR: Neonatal Champagne Lumbar punctures Every time – An RCT: a multicentre, randomised controlled 2?×?2 factorial trial to investigate techniques to increase lumbar puncture success. BMC Pediatrics. 2020;20(1):165.
https://doi.org/10.1186/s12887-020-02050-8

Show Lumbar Puncture Training Videos

Lying with Early Stylet Removal

Lying with Late Stylet Removal

Sitting with Early Stylet Removal

Sitting with Late Stylet Removal

Holding for Lying and Sitting Neonatal Lumbar Punctures

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