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Record month for Poppi

Fantastic effort from the Poppi team at the JR in Oxford, they have broken the Poppi recruitment record by recruiting 5 participants this month, bringing our total up to 19 participants! Thank you to all the families who have agreed to take part, and congratulations to the Poppi team - keep up the great work!

New publication for Poppi investigators

Dr Caroline Hartley and the rest of the PIPA group have published an article validating the measure of infant nociceptive brain activity used in the Poppi trial. Validation of these approaches is important to ensure that nociceptive brain activity can be interpreted accurately, so effective pain relief measures can be developed for the infant population.

This publication has caused huge interest from the media – articles about the team (led by Dr Rebeccah Slater), and their work, have been published in the New Scientist and on IEEE Spectrum.

An interview with Dr Rebeccah Slater about the work of the group is also available on the International business times UK website.

View Caroline Hartley's publication on the Science Translational Medicine website.

Poppi Trial reaches 6 months’ recruitment

The Poppi Trial, led by Dr Eleri Adams and Dr Rebeccah Slater and supported by SSNAP (Support for the Sick Newborn And their Parents), has now been open for 6 months! This trial is running at the John Radcliffe Hospital in Oxford, and the Poppi team here have worked incredibly hard to recruit 11 babies so far. Thank you to all the families taking part, and great job Poppi team - keep up the good work!

Poppi Trial Protocol published on Wellcome Open Research

The protocol for the Poppi Trial (Procedural Pain in Premature Infants) has been published on the Wellcome Open Research platform. The protocol documents the background, rationale, methods and design of the trial. The Poppi trial, which aims to establish whether oral morphine provides effective analgesia for procedural pain in infants, is led by Dr Eleri Adams and Dr Rebeccah Slater in collaboration with the NPEU and the Paediatric and Infant Pain & Anaesthesia (PiPA) group. You can read the protocol now for more details about the trial. Our congratulations go out to the entire Poppi Trial team.

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The Poppi trial is funded by The Wellcome Trust and the NIHR EME Programme.

NIHR acknowledgment and disclaimer: This study is funded by the National Institute for Health Research (NIHR) Efficacy and Mechanism Evaluation (EME) Programme (Reference Number 14/187/01). The views expressed are those of the author(s) and not necessarily those of the NIHR or the Department of Health and Social Care.