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Heather O'Connor BSc (Hons) MSc

Senior Statistician


I joined the NPEU CTU as a Senior Statistician in July 2022. Within my role I take lead responsibility for the statistical aspects of the design, analysis and reporting of trials/studies in the NPEU portfolio. This involves working collaboratively with internal and external collaborators, providing statistical input in the development of grant funding applications, study protocols/documentation, and data collection instruments/tools

Before this role I spent a year within the Modernising Medical Microbiology consortium in the Nuffield Department of Medicine's Experimental Medicine team, working as a Senior Medical Statistician and developing analyses to address important questions around the epidemiology and management of COVID-19. Prior to this I spent three years as a Medical Statistician at the Oxford Clinical Trials Research Unit (OCTRU) within the Centre for Statistics in Medicine (CSM), working on clinical trials of various stages.

With a background in collaborative and mixed-methods research, I am passionate about applying my statistical skills in a useful and meaningful way, making sense of the complex, and transferring knowledge from evidence-based research to all those it may affect. I am particularly passionate about science with impact, working to integrate findings from robust research into advice, guidelines, and policy.


Dickenson, E., Griffin, X.L., Achten, J., Mironov, K., O'Connor, H., Parsons, N., Murphy, M., Wyse, M., Mason, J., Appelbe, D., Athwal, A., Griffin, D. Randomised controlled trial comparing intraoperative cell salvage and autotransfusion with standard care in the treatment of hip fractures: a protocol for the WHITE 9 study. BMJ Open 2022; 12:e062338. doi: 10.1136/bmjopen-2022-062338

Nanchahal, J., Ball, C., Rombach, I., Williams, L., Kenealy, N., Dakin, H., O'Connor, H., Davidson, D., Werker, P., Dutton, S.J., Feldmann, M., Lamb, S.E. Anti-tumour necrosis factor therapy for early-stage Dupuytren's disease (RIDD): a phase 2b, randomised, double-blind, placebo-controlled trial. The Lancet Rheumatology; 4(6): 2022, e407-e416, ISSN 2665-9913,

Griffin, X., Achten, J., O'Connor, H.M., Cook, J., Costa, M. 2021. Effect of the X-Bolt dynamic plating system versus the sliding hip screw for the fixation of trochanteric fractures of the hip in adults on health-related quality of life: the WHiTE Four randomized clinical trial. Bone and Joint Journal. 103-B:2, 256-263

Harrison, P., Didembourg, M., Wood, A., Devi, A., Dinsdale, R., Hazeldine, J., Alsousou, J., Keene, D., Hulley, P., Wagland, S., Parsons, S., Thompson, J., Byrne, C., Schlussel, M.M., O'Connor, H., Dutton, S., Lamb, S., and Willett, K. 2020. Characteristics of L-PRP preparations for treating Achilles Tendon Rupture within the PATH-2 study. Platelets. Feb 17;32(2):273-279

Alsousou J., Keene D., Harrison P., Hulley P., Wagland S., Thompson J., Byrne C., Schlüssel M., O'Connor H.M., Dutton S. et al. 2019. Platelet-rich plasma injection for adults with acute Achilles tendon rupture: the PATH-2 RCT. Efficacy and Mechanism Evaluation 6(12):18 Dec 2019

Stubberfield E., AbuOun M., Sayers E., O'Connor, H.M., Card R.M., Anjum MF. 2019. Use of whole genome sequencing of commensal Escherichia coli in pigs for antimicrobial resistance surveillance, United Kingdom, 2018. Eurosurveillance 24(50):13 Dec 2019

Keene D., Alsousou J., Harrison P., Hulley P., Wagland S., Parsons S., Thompson J., O'Connor H.M., Schlüssel M.M., Dutton S. et al. 2019. Platelet rich plasma injection for acute Achilles tendon rupture: PATH-2 randomised, placebo controlled, superiority trial. BMJ 367:l6132

Francis E., Ball C., Barber V., O'Connor H.M., Dutton S., Lamb S., Nanchahal J., Condon D. 2019. A successful strategy for recruiting participants not in a care pathway to a CTIMP on time and to target. Trials. BioMed Central. 20

Richens I.F., Houdmont J., Wapenaar W., Shortall O., Kaler J., O'Connor H.M., Brennan M.L. 2018. Application of multiple behaviour change models to identify determinants of farmers' biosecurity attitudes and behaviours. Preventive Veterinary Medicine 155:61-74

Brunton, L.A., Donnelly, C.A., O'Connor, H.M., Prosser, A., Ashfield, S., Ashton, A., Upton, P., Mitchell, A., Goodchild, A.V., Parry, J.E. & Downs, S.H. 2017. Assessing the effects of the first 2 years of industry-led badger culling in England on the incidence of bovine tuberculosis in cattle in 2013–2015. Ecology and Evolution 7(18): 7213-7230

Brennan, M.L., Wright, N., Wapenaar, W., Jarratt, S.; Hobson-West, P., Richens, I.F., Kaler, J., Buchanan, H., Huxley, J.N., O'Connor, H.M. 2016. Exploring Attitudes and Beliefs towards Implementing Cattle Disease Prevention and Control Measures: A Qualitative Study with Dairy Farmers in Great Britain. Animals 6(61)

Drewe,J.A., O'Connor,H.M., Weber, N., McDonald, R.A. & Delahay, R.J. 2013. Patterns of direct and indirect contact between cattle and badgers naturally infected with tuberculosis. Epidemiology and Infection 141(7): 1467-75