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Effects of prenatal alcohol consumption and alcohol metabolising genes on child growth and neurodevelopment in the ALSPAC study

Principal investigator
Ron Gray (NPEU (Former member))
Collaborators
David Nutt (University of Bristol), Sarah Lewis (University of Bristol), Jean Golding (University of Bristol), Robert Fraser (University of Sheffield), Elizabeth Draper (University of Leicester), George Davey Smith (University of Bristol), Margaret Barrow (University of Leicester), Rosa Alati (University of Queensland, Australia)
Topics
Alcohol in pregnancy
Funder
Wellcome
Start year
2008
End year
2010
NPEU Contact
Jenny Kurinczuk

Summary

This study commencing in March 2008 examined the effect of prenatal alcohol consumption (and polymorphisms of several of the genes coding for enzymes involved in alcohol metabolism) on child growth and neurodevelopment. We used an extended mendelian randomisation approach to examine the unconfounded effects of alcohol consumption on the fetus. The study used the well characterised ALSPAC cohort.

Publications

Journal Articles