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EUPHRATES trial - trial of blood collector bag in third stage of labour

Principal investigator
Sophie Alexander (Universite Libre de Bruxelles, Brussels)
Jos van Roosmalen (Leiden University Hospital, Leiden, Netherlands), Babil Stray-Pedersen (The National Hospital, Oslo, Norway), Jette Sorensen (Hvidovre Hospital, Copenhagen, Denmark), Walter Prendiville (RCSI Department of Gynaecology, Dublin, Eire), Anna Maria Marconi (Universita Degli Studi di Milano, Milano, Italy), Alison Macfarlane (City University, London), Jens Langhoff-Roos (Rigshopitalet Dept of Obstetrics and Gynaecology, Copenhagen, Denmark), Mathias Klein (Hanusch-Krankenhaus Gynakolog U, Vienna, Austria), Wolfgang Holzgreve (Kantonsspital Basel, Basel, Switzerland), Edwige Haelterman (Universite Libre de Bruxelles, Brussels), Risto Erkkola (Univeristy Central Hospital of Turku, Turku, Finland), Luigi Chiechi (University of Bari, Bari, Italy), Vincenc Cararach (Hospital Clinic, Barcelona, Spain), Marie-Helene Bouvier-Colle (INSERM U149, France), Istvan Berbik (Petofi SU 26, Esztergom, Hungary), Diogo Ayers De Campos (Faculdade de Medicina do Porto, Porto, Portugal), Peter Brocklehurst (NPEU), Ed Juszczak (NPEU)
Labour and delivery
European funding
Start year
End year
NPEU Contact
Ed Juszczak


The aim of this EU project was to tackle the problem of obstetric haemorrhage by a multi-mode approach. Obstetric haemorrhage is still responsible for maternal deaths and severe morbidity in Europe. The project had several aims: (a) to document current clinical practice in relation to management of the third stage of labour and the management of established haemorrhage, (b) to establish a consensus on minimal management, (c) mount a randomised controlled trial of a blood-collecting device to be used at the time of delivery to accurately measure blood loss and (d) and (e) establish websites for clinicians and women respectively. These activities are now finished and reports of the survey of practice and the consensus statement have been published. The report of the randomised controlled trial has been published in the BMJ.


Journal Articles