EUROCAT - European Surveillance of Congenital Anomalies - Survey of prenatal diagnosis screening methods across Europe Perinatal screening for birth defects in Europe - a EUROCAT study of the impact of different national policies

Principal investigators: Helen Dolk (University of Ulster), Patricia Boyd (NPEU (Former member))
Collaborators: Catherine Rounding (NPEU (Former member))
Topics: Labour and delivery
Funders: DH Registers, European funding
Start year: 2005
End year: 2010
NPEU Contact: Jenny Kurinczuk

Summary

EUROCAT is an EU funded project to which CAROBB along with other European congenital anomaly registers submit data and collaborates in a series of different studies (1.3.7, 1.3.11).On-going collaborations include studies on, for example, neural tube defects and unbalanced chromosome anomalies. Through EUROCAT CAROBB data are also being used in a study of facial clefts by the International Clearing House for Birth Defects.

Publications

Journal Articles

Greenlees R, Neville A, Addor MC, Amar E, Arriola L, Bakker M, Barisic I, Boyd PA, Calzolari E, Doray B, Draper E, Emil Vollset S, Garne E, Gatt M, Haeusler M, Kallen K, Khoshnood B, Latos?Bielenska A, Martinez?Frias ML, Materna?Kiryluk A, Matias Dias C, McDonnell B, Mullaney C, Nelen V, O'Mahony M, Pierini A, Queisser?Luft A, Randrianaivo?Ranjato?lina H, Rankin J, Rissmann A, Ritvanen A, Salvador J, Sipek A, Tucker D, Verellen?Dumoulin C, Wellesley D, Wertelecki W. Paper 6: EUROCAT member registries: Organization and activities. Birth Defects Res A Clin Mol Teratol. 2011;91(S1):S51-S100.
Loane M, Morris JK, Addor MC, Arriola L, Budd J, Doray B, Garne E, Gatt M, Haeusler M, Khoshnood B, Klungsoyr Melve K, Latos-Bielenska A, McDonnell B, Mullaney C, O'Mahony M, Queisser-Wahrendorf A, Rankin J, Rissmann A, Rounding C, Salvador J, Tucker D, Wellesley D, Yevtushok L, Dolk H. Twenty-year trends in the prevalence of Down syndrome and other trisomies in Europe: impact of maternal age and prenatal screening. Eur J Hum Genet. 2013;21(1):27-33.
Wellesley D, Dolk H, Boyd PA, Greenlees R, Haesler M, Nelen V, Garne E, Khoshnood B, Doray B, Rissmann A, Mullaney C, Calzolari E, Bakker M, Salvador J, Addor MC, Draper E, Rankin J, Tucker D. Rare chromosome abnormalities, prevalence and prenatal diagnosis rates from population-based congenital anomaly registers in Europe. Eur J Hum Genet. 2012;20(5):521-6.
Barisic I, Odak L, Loane M, Garne E, Wellesley D, Calzolari E, Dolk H, Addor MC, Arriola L, Bergman J, Bianca S, Boyd PA, Draper ES, Gatt M, Haeusler M, Khoshnood B, Latos-Bielenska A, McDonnell B, Pierini A, Rankin J, Rissmann A, Queisser-Luft A, Verellen-Dumoulin C, Stone D, Tenconi R. Fraser syndrome: epidemiological study in a European population. Am J Med Genet A. 2013;161A(5):1012-8.
Boyle B, McConkey R, Garne E, Loane M, Addor MC, Bakker MK, Boyd PA, Gatt M, Greenlees R, Haeusler M, Klungsoyr K, Latos-Bielenska A, Lelong N, McDonnell R, Metneki J, Mullaney C, Nelen V, O'Mahony M, Pierini A, Rankin J, Rissmann A, Tucker D, Wellesley D, Dolk H. Trends in the prevalence, risk and pregnancy outcome of multiple births with congenital anomaly: a registry-based study in 14 European countries 1984-2007. BJOG. 2013;120(6):707-16.
Boyle B, Morris JK, McConkey R, Garne E, Loane M, Addor MC, Gatt M, Haeusler M, Latos-Bielenska A, Lelong N, McDonnell R, Mullaney C, O'Mahony M, Dolk H. Prevalence and risk of Down syndrome in monozygotic and dizygotic multiple pregnancies in Europe: implications for prenatal screening. BJOG. 2014;121(7):809-19; discussion 20.
Calzolari E, Barisic I, Loane M, Morris J, Wellesley D, Dolk H, Addor MC, Arriola L, Bianchi F, Neville AJ, Budd JL, Klungsoyr K, Khoshnood B, McDonnell B, Nelen V, Queisser-Luft A, Rankin J, Rissmann A, Rounding C, Tucker D, Verellen-Dumoulin C, de Walle H, Garne E. Epidemiology of multiple congenital anomalies in Europe: a EUROCAT population-based registry study. Birth Defects Res A Clin Mol Teratol. 2014;100(4):270-6.