A population-based national study of the surgical outcomes of infants born with duodenal atresia.
Marian Knight (NPEU)
Nigel Hall (NPEU (Former member)), Anna-May Long (NPEU (Former member))
National Institute for Health Research
This study will use BAPS-CASS to conduct a prospective, national observational investigation of the incidence, current management practices and outcomes of infants born with duodenal atresia or stenosis in the UK and Ireland.
Any live-born infant with occlusion or narrowing of the duodenum associated with atresia, stenosis, duodenal web or annular pancreas presenting before 44 weeks post-conception will be included.
Infants with occlusion of the duodenum caused by congenital bands associated with malrotation, intestinal volvulus, duplication cyst or malignancy will be excluded.
Selected Research Questions
What is the current incidence of live-born duodenal-atresia or stenosis in the UK or Ireland?
How are these infants managed?
What is the incidence of associated abnormalities in live-born infants?
What is the impact of comorbidity on outcome?
What are the outcomes for infants managed with and without a trans-anastomotic tube?
What are the outcomes following different surgical techniques for repair of duodenal atresia or stenosis?