BAPS-CASS - A population-based national study of surgical outcomes of infants born with gastroschisis
- Principal investigators
- Sean Marven (Sheffield Children's Hospital), Marian Knight (NPEU)
- Collaborators
- Anthony Owen (Sheffield Children's Hospital), Paul Johnson (Oxford Children's Hospital), Elizabeth Draper (University of Leicester), Jenny Kurinczuk (NPEU)
- Topics
- Congenital anomalies, Paediatric surgery
- Funders
- British Association of Paediatric Surgeons, BDF Newlife
- Start year
- 2006
- End year
- 2010
- NPEU Contact
- Marian Knight
Summary
The aim of this project was to describe the current surgical management and outcomes of infants with gastroschisis in the UK. The incidence of gastroschisis, a congenital anomaly of the anterior abdominal wall, has been noted to be increasing in the UK and worldwide. A number of uncertainties exist about different surgical management options, including particularly staged versus primary closure and the use of preformed silos. This study showed that operative primary closure and staged closure after a preformed silo were the most commonly used intended surgical techniques for simple gastroschisis. Outcomes for infants with complex gastroschisis were significantly poorer than for simple cases, although all deaths occurred in the simple group.
Publications
Journal Articles
- Owen A, Marven S, Johnson P, Kurinczuk J, Spark P, Draper ES, Brocklehurst P, Knight M. Gastroschisis: a national cohort study to describe contemporary surgical strategies and outcomes. J Pediatr Surg. 2010;45(9):1808-16.
- Bradnock TJ, Marven S, Owen A, Johnson P, Kurinczuk JJ, Spark P, Draper ES, Knight M. Gastroschisis: one year outcomes from national cohort study. Br Med J. 2011;343:d6749.