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Kate Fitzpatrick BA (Hons), MSc, DPhil

Senior Researcher in Statistical Epidemiology kate.fitzpatrick@npeu.ox.ac.uk

Biography

Kate is a Senior Researcher in Statistical Epidemiology based in the National Perinatal Epidemiology Unit (NPEU). She has a particular interest in using routinely collected data to inform the care and improve outcomes for mothers, babies and their families across the life-course.

In 2016 she was awarded a National Institute for Health Research (NIHR) Doctoral Research Fellowship to undertake a DPhil part-time at the University of Oxford. Her DPhil investigated the short and longer-term outcomes for women and their children according to planned mode of birth after previous caesarean section using a number of linked Scottish National datasets.

Kate recently led a Wellbeing of Women funded multi-country study that used the International Network of Obstetric Survey Systems to investigate the risk factors, management and associated outcomes of Amniotic Fluid Embolism (AFE), a rare pregnancy complication that remains one of the leading causes of direct maternal mortality in high income countries. She has previously conducted a number of national case-control and cohort studies examining various pregnancy and birth-related complications using the UK Obstetric Surveillance System. She has also previously been involved in several international multi-centre research projects seeking to investigate how genetic variation affects the biology and epidemiology of malaria, and research investigating the epidemiology of various eye diseases in India. She has a degree in Biological Sciences from the University of Oxford and a Masters in Epidemiology from the London School of Hygiene and Tropical Medicine.

Publications

Fitzpatrick KE, Kurinczuk JJ, Quigley MA (2021). Planned mode of birth after previous caesarean section and special educational needs in childhood: a population-based record linkage cohort study. BJOG 2021; https//doi.org/10.1111/1471-0528.16828

Fitzpatrick KE, Quigley MA, Smith DJ, Kurinczuk JJ (2021). Planned mode of birth after previous caesarean section and women's use of psychotropic medication in the first year postpartum: a population-based record linkage cohort study. Psychological Medicine 1–12. https://doi.org/10.1017/ S0033291720005322

Fitzpatrick KE, Van den Akker T, Bloemenkamp KWM, Deneux-Tharaux C, Kristufkova A, Li Z, Schapp TP, Sullivan EA, Tuffnell D, Knight M. Risk factors, management, and outcomes of amniotic fluid embolism: A multicounty, population-based cohort and nested case-control study. PLoS Medicine 2019; 16(11): e1002962

Fitzpatrick KE, Kurinczuk JJ, Bhattacharya S, Quigley MA. Planned mode of delivery after previous cesarean section and short-term maternal and perinatal outcomes: A population-based record linkage cohort study in Scotland. PLoS Medicine 2019; 16(9): e1002913

The Malaria Genomic Epidemiology Network. Human candidate gene polymorphisms and risk of severe malaria in children in Kilifi, Kenya: a case-control association study. The Lancet Haematology 2018; 5, e333 - e345

Fitzpatrick KE, Tuffnell D, Kurinczuk JJ, Knight M. Pregnancy at very advanced maternal age: a UK population-based cohort study. BJOG 2016; DOI: 10.1111/1471-0528.14269.

Knight M, Ancosta C, Brocklehurst P, Cheshire A, Fitzpatrick K, Hinton L, et al. Beyond maternal death: Improving the quality of maternal care through national studies of near-miss maternal morbidity. Programme Grants for Applied Research 2016;4(9)

Fitzpatrick KE, Grey R, Quigley MA. Women's longitudinal patterns of smoking during the pre-conception, pregnancy and postnatal period: evidence from the UK Infant Feeding Survey. PLoS One 2016; 11(4):e0153447.

The Malaria Genomic Epidemiology Network. Admixture into and within sub-Saharan Africa. eLife 2016; 5:e15266; DOI: 10.7554/eLife.15266

Fitzpatrick KE, Tuffnell D, Kurinczuk JJ, Knight M. Incidence, risk factors, management and outcomes of amniotic-fluid embolism: a population-based cohort and nested case-control study. BJOG 2015; DOI: 10.1111/1471-0528.13300.

The Malaria Genomic Epidemiology Network. A novel locus of resistance to severe malaria in a region of ancient balancing selection. Nature 2015; 526: 253-7

Fitzpatrick KE, Sellers S, Spark P, Kurinczuk JJ, Brocklehurst P, Knight M. Author's reply: The morbidly adherent placenta (MAP): early accurate diagnosis is essential for the meaningful interpretation of outcomes. BJOG 2014; DOI:10.1111/1471-0528.12919.

Fitzpatrick KE, Hinshaw K, Kurinczuk JJ, Knight M. Risk Factors, Management and Outcomes of Hemolysis, Elevated Liver Enzymes, and Low Plateles Syndrome and Elevated Liver Enzymes, Low Platelets Syndrome. Obstetrics & Gynecology 2014 Mar;123(3):618-27. doi: 10.1097/AOG.0000000000000140.

The Malaria Genomic Epidemiology Network. Reapprasial of known malaria resistance loci in a large multicenter study. Nature Genetics 2014; 46(11): 1197-204. doi: 10.1038/ng.3107.

Fitzpatrick KE, Sellers S, Spark P, Kurinczuk JJ, Brocklehurst P, Knight M. The Management and Outcomes of Placenta Accreta/Increta/Percreta in the UK: A Population-based Descriptive Study. BJOG 2013; DOI:10.1111/1471-0528.12405

Fitzpatrick KE, Sellers S, Spark P, Kurinczuk JJ, Brocklehurst P, Knight M. Incidence and Risk Factors for Placenta Accreta/Increta/Percreta in the UK: A National Case-Control Study. PLoS One 2012;7(12):e52893

Knight M, Fitzpatrick KE, Kurinczuk JJ, Tuffnell Derek. Use of recombinant factor VIIa in patients with amniotic fluid embolism. Anesthesiology 2012; 117(2): 423; author reply 423-4. doi: 10.1097/ALN.0b013e31825b6c77

Fitzpatrick KE, Kurinczuk JJ, Alfirevic Z, Spark P, Brocklehurst P, Knight M. Uterine Rupture by Intended Mode of Delivery in the UK: A National Case-Control Study. PLoS Medicine 2012; 9(3): e1001184

Ravindran RD, Vashist P, Gupta SK, Young IS, Maraini G, Camparini M, Jayanthi R, John N, Fitzpatrick KE, Chakravarthy U, Ravilla TD, Fletcher AE. Prevalence and risk factors for vitamin C deficiency in north and south India: a two centre population based study in people aged 60 years and over. PLoS One 2011; 6(12): e28588

Ravindran RD, Vashist P, Gupta SK, Young IS, Maraini G, Camparini M, Jayanthi R, John N, Fitzpatrick KE, Chakravarthy U, Ravilla TD, Fletcher AE. Inverse association of vitamin C with Cataract in older people in India. Ophthalmology 2011; 118(10):1958-1965.e2

Vashist P, Talwar B, Gogoi M, Maraini G, Camparini M, Ravindran RD, Murthy GV, Fitzpatrick KE, John N, Chakravarthy U, Ravilla TD, Fletcher AE. Prevalence of Cataract in an Older Population in India: The India Study of Age-related Eye Disease. Ophthalmology 2011; 118(2):272-8.e1-2

Krishnan T, Ravindran RD, Murthy GV, Vashist P, Fitzpatrick KE, Thulasiraj RD, John N, Maraini G, Camparini M, Chakravarthy U & Fletcher AE. Prevalence of Early and Late Age-Related Macular Degeneration in India: The INDEYE Study. Investigative Ophthalmology & Visual Science 2010; 51(2):701-7

The Malaria Genomic Epidemiology Network. A global network for investigating the genomic epidemiology of malaria. Nature 2008; 456: 732-737