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Dr Reem Malouf MD, MSc, Neurologist, Specialist in Internal Medicine, ABMS

Health services researcher & Teaching fellow


I joined the NPEU in 2011 to look at maternity services for women with disability. I have been involved in a number of projects, including the neuro-development of children born prematurely and preterm birth clinics. I am particularly interested in research around maternal mental health and well-being.

I am a clinically trained neurologist with a masters in medical statistics. I previously worked as a research fellow at St George's Hospital in London. I have authored several Cochrane reviews, mainly in the field of cognitive improvement and dementia, haematology and oncology. I am a co-founder of ALOIS, an online register of dementia studies, an editor of the Cochrane Lung Cancer group, and a member of Cochrane methods and living systematic reviews network groups.


Hamilton EM, Rassam W, Yan Y, Singh A, Ng SYA, Zhang J, Lv J, Islam N, Malouf R, Yang L, Millwood IY, Chen Z. Correlates of chronic hepatitis B virus infection in the general adult population of China: systematic review and meta-analysis. J Viral Hepat. 2023;doi:10.1111/jvh.13816.

Bonney A, Malouf R, Marchal C, Manners D, Fong KM, Marshall HM, Irving LB, Manser R. Impact of low-dose computed tomography (LDCT) screening on lung cancer-related mortality. Cochrane Database Syst Rev. 2022;8(8):Cd013829.

Malouf R, Harrison S, Burton HAL, Gale C, Stein A, Franck LS, Alderdice F. Prevalence of anxiety and post-traumatic stress (PTS) among the parents of babies admitted to neonatal units: A systematic review and meta-analysis. EClinicalMedicine. 2022;43:101233.

Ferrara R, Imbimbo M, Malouf R, Paget-Bailly S, Calais F, Marchal C, Westeel V. Single or combined immune checkpoint inhibitors compared to first-line platinum-based chemotherapy with or without bevacizumab for people with advanced non-small cell lung cancer. Cochrane Database Syst Rev. 2021;4:Cd013257.

Ayman G, Strachan JA, McLennan N, Malouf R, Lowe-Zinola J, Magdi F, Roberts N, Alderdice F, Berneantu I, Breslin N, Byrne C, Carnell S, Churchill D, Grisoni J, Hirst JE, Morris A, Murphy HR, O'Brien J, Schmutz C, Shah K, Singal AS, Strachan MWJ, Cowan K, Knight M. The top 10 research priorities in diabetes and pregnancy according to women, support networks and healthcare professionals. Diabet Med. 2021;38(8):e14588.

Malouf RS, Tomlinson C, Henderson J, Opondo C, Brocklehurst P, Alderdice F, Phalguni A, Dretzke J. Impact of obstetric unit closures, travel time and distance to obstetric services on maternal and neonatal outcomes in high-income countries: a systematic review. BMJ Open. 2020;10(12):e036852.

Alderdice F, McLeish J, Henderson J, Malouf R, Harvey M, Redshaw M. Women's ideal and real expectations of postnatal care during their first pregnancy: An online survey in England. Midwifery. 2020;89:102815.

Malouf R, Ashraf A, Hadjinicolaou AV, Doree C, Hopewell S, Estcourt LJ. Comparison of a therapeutic-only versus prophylactic platelet transfusion policy for people with congenital or acquired bone marrow failure disorders. Cochrane Database of Systematic Reviews. 2018;10.1002/14651858.CD012342.pub2(5).

Estcourt LJ, Malouf R, Murphy MF. Pathogen-reduced platelets for the prevention of bleeding in people of any age. JAMA Oncology. 2018;4(4):571-2.

Malouf R, Redshaw M. Specialist antenatal clinics for women at high risk of preterm birth: a systematic review of qualitative and quantitative research. BMC Pregnancy and Childbirth. 2017;17(1):51.

Malouf R, McLeish J, Ryan S, Gray R, Redshaw M. 'We both just wanted to be normal parents': a qualitative study of the experience of maternity care for women with learning disability. BMJ Open. 2017;7(3).

Malouf R, Henderson J, Redshaw M. Access and quality of maternity care for disabled women during pregnancy, birth and the postnatal period in England: data from a national survey. BMJ Open. 2017;7(7):e016757.

Linsell L, Malouf R, Morris J, Kurinczuk JJ, Marlow N. Risk Factor Models for Neurodevelopmental Outcomes in Children Born Very Preterm or With Very Low Birth Weight: A Systematic Review of Methodology and Reporting. American Journal of Epidemiology. 2017;185(7):601-12.

Estcourt LJ, Malouf R, Trivella M, Fergusson DA, Hopewell S, Murphy MF. Restrictive versus liberal red blood cell transfusion strategies for people with haematological malignancies treated with intensive chemotherapy or radiotherapy, or both, with or without haematopoietic stem cell support. Cochrane Database of Systematic Reviews. 2017;10.1002/14651858.CD011305.pub2(1).

Estcourt LJ, Malouf R, Hopewell S, Trivella M, Doree C, Stanworth SJ, Murphy MF. Pathogen-reduced platelets for the prevention of bleeding. The Cochrane database of systematic reviews. 2017;7:CD009072-CD.

Estcourt LJ, Malouf R, Doree C, Trivella M, Hopewell S, Birchall J. Prophylactic platelet transfusions prior to surgery for people with a low platelet count. Cochrane Database of Systematic Reviews. 2017;10.1002/14651858.CD012779(9).

Coxon K, Chisholm A, Malouf R, Rowe R, Hollowell J. What influences birth place preferences, choices and decision-making amongst healthy women with straightforward pregnancies in the UK? A qualitative evidence synthesis using a 'best fit' framework approach. BMC Pregnancy and Childbirth. 2017;17(1):103.

Linsell L, Malouf R, Morris J, Kurinczuk JJ, Marlow N. Prognostic factors for cerebral palsy and motor impairment in children born very preterm or very low birthweight: a systematic review. Developmental Medicine & Child Neurology. 2016;58(6):554-69.

Hollowell J, Li Y, Malouf R, Buchanan J. Women's birth place preferences in the United Kingdom: a systematic review and narrative synthesis of the quantitative literature. BMC Pregnancy and Childbirth. 2016;16:213.

Chan E, Leong P, Malouf R, Quigley MA. Long-term cognitive and school outcomes of late-preterm and early-term births: a systematic review. Child: Care, Health and Development. 2016;42(3):297-312.

Linsell L, Malouf R, Morris J, Kurinczuk JJ, Marlow N. Prognostic Factors for Poor Cognitive Development in Children Born Very Preterm or With Very Low Birth Weight: A Systematic Review. JAMA Pediatrics. 2015;169(12):1162-72.

Linsell L, Malouf R, Johnson S, Morris J, Kurinczuk JJ, Marlow N. Prognostic Factors for Behavioral Problems and Psychiatric Disorders in Children Born Very Preterm or Very Low Birth Weight: A Systematic Review. J Dev Behav Pediatr. 2015;37(1):88-102.

Malouf R, Redshaw M, Kurinczuk JJ, Gray R. Systematic review of health care interventions to improve outcomes from women with disability and their family during pregnancy, birth and postnatal period. BMC Pregnancy and Childbirth. 2014;14(1):58.

Redshaw M, Malouf R, Gao H, Gray R. Women with disability: the experience of maternity care during pregnancy, labour and birth and the postnatal period. BMC Pregnancy Childbirth. 2013;13:174.

Moniz Cook ED, Roberts-Stride K, James I, Malouf R, De Vugt M, Verhey F. Challenging Behaviour In Dementia: Functional Analysis-Based Interventions. Cochrane library 2011.

Dudas R, Malouf R, Jatinder Bains, Jacqueline Birks, Tom Dening. Antidepressants for treating depression in dementia. Cochrane library 2010.

Bernadette McGuinness, David Craig, Roger Bullock, Reem Malouf, Peter Passmore Statins for the treatment of Alzheimer's disease and dementia. Cochrane 2010

Geng J, Dong J, Ni H, Lee MS, Wu T, Jiang K, Wang G, Zhou AL, Malouf R. Ginseng for cognition (Cochrane library, issue 4, 2010)

Reily S, Rmalouf Etal : Case management approaches to home support for people with dementia. Cochrane library 2010, issue 2

Reem Malouf, Helen Collins. Tramiprosate (Alzhemed) for Alzheimer's disease. Cochrane Database of Systematic Reviews, Issue 2, 2009

David Craig, Reem Malouf, Jacqueline Birks. Galantamine for vascular cognitive impairment. Cochrane library. 2009.

Grimley-Evans J, Malouf R. Dehydroepiandrosterone (DHEA) supplementation for cognitive function in healthy elderly people Cochrane review 2006. Cochrane Database of Systematic Reviews 2006, Issue 4

Malouf RS, Grimley-Evans J. The effect of vitamin B6 on cognition. Cochrane Protocol Review 2006

Malouf RS, Birks J. Donepezil and vascular cognitive impairment Cochrane Review May 2006

Adams N, Malouf R, Jones P. Inhaled beclomethasone at different doses for chronic asthma Cochrane review 2004

Malouf RS, Areosa AM. The effects of vitamin B12 on cognition. Cochrane Review Library May 2003

Malouf RS, Areosa AM. The effect of folic acid with or without vitamin B12 on cognition. Cochrane Review February 2003

Clive G Ballard, Reem Malouf, Jonathan Waite, Jacqueline Birks. Atypical antipsychotics for aggression and psychosis in Alzheimer's disease (drafting the update)

Schneider L, Malouf R, Collins H. Cholinesterase inhibitors and memantine for analysis of deaths in vascular dementia and Alzheimer's disease. Protocol.

Malouf R etal: ALOIS: Alzheimer's and cognitive improvement studies register, a free, on-line register of dementia and cognitive enhancement trials (

Alzheimer's & Dementia: The Journal of the Alzheimer's Association , Volume 5 , Issue 4 , P251 - P252