Associate Professor Ramon Luengo-Fernandez

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Associate Professor - Senior Researcher in Health Economics ramon.luengo-fernandez@dph.ox.ac.uk

Biography

Ramon joined the NPEU as a Senior Health Economist in October 2023 working previously at the Health Economics Research Centre (HERC), University of Oxford during the period 2004-2023. He is part of a team of four researchers involved in a programme of work conducting economic evaluations and health economic analyses in maternal and child health. He has extensive experience using experimental and observational data, and evidence synthesis decision analytic models to inform cost-effectiveness evaluations. His programme of work also includes studies estimating the long-term healthcare costs and outcomes in numerous diseases, most notably stroke. He is actively involved in teaching and postgraduate supervision and has experience of sitting in National Institute for Health Research panels. Ramon divides his time between NPEU and the Wolfson Centre for Prevention of Stroke and Dementia (Nuffield Department of Clinical Neurosciences, University of Oxford).

Publications

Luengo-Fernandez R, Walli-Attaei M, Gray A, Torbica A, Maggioni AP, Huculeci R, Bairami F, Aboyans V, Timmis AD, Vardas P, Leal J. Economic burden of cardiovascular diseases in the European Union: a population-based cost study. European Heart Journal 2023; doi/10.1093/eurheartj/ehad583/7251239

Luengo-Fernandez R, Little M, Gray A, Torbica A, Maggioni AP, Huculeci R, Timmis AD, Vardas P, Leal J. Cardiovascular disease burden due to productivity losses in European Society of Cardiology countries. European Heart Journal – Quality of Care and Clinical Outcomes 2023;10.1093/ehjqcco/qcad031

Candio P, Violato M, Luengo-Fernandez R, Leal J. Cost-effectiveness of home-based stroke rehabilitation across Europe: A modelling study. Health Policy 2022;126:183-189.

Luengo-Fernandez R, Landeiro F, Hallifax R, Rahman NM. Cost-effectiveness of ambulatory care management of primary spontaneous pneumothorax: an open-label, randomised controlled trial. Thorax 2022; http://dx.doi.org/10. 1136/thoraxjnl-2021-218479

Luengo-Fernandez R, Li L, Silver L, Gutnikov S, Beddows NC, Rothwell PM. Long-term impact of urgent secondary prevention after transient ischaemic attack and minor stroke: ten-year follow-up of the EXPRESS study. Stroke 2022;53:488-496.

Psallidas I, Hassan M, Yousuf A, Duncan T, Khan SS, Blyth KG, Evison M, Corcoran P, Barnes S, Reddy R, Bonta PI, Bhatnagar R, Kagithala G, Dobson M, Knight R, Dutton SJ, Luengo-Fernandez R, Hedley E, Piotrowska H, Brown L, Asa'ari KA, Mercer RM, Asciack R, Bedawi EO, Hallifax RJ, Slade M, Benamore R, Edey A, Miller RF, Maskell NA, Rahman NM. Role of thoracic ultrasonography in pleurodesis pathways for malignant pleural effusions (SIMPLE): an open-label, randomised controlled trial. Lancet Respir Med 2022;10:139-148

Candio F, Violato M, Leal J, Luengo-Fernandez R. Cost-effectiveness of mechanical thrombectomy for treatment of non-minor ischaemic stroke across Europe. Stroke 2021;52:664-673.

Luengo-Fernandez R, Li L, Rothwell PM. Costs of bleeding on long-term antiplatelet treatment without routine co-prescription of proton pump inhibitors. International Journal of Stroke 2021;16:719-726.

Ganesh A, Luengo-Fernandez R, Rothwell PM. Late functional improvement and 5-year poststroke outcomes: a population-based cohort study. Journal of Neurology, Neurosurgery & Psychiatry 2020;91:831-839.

Ganesh A, Luengo-Fernandez R, Pendlebury ST, Rothwell PM. Weights for ordinal analyses of the modified Rankin Scale in stroke trials: a population-based cohort study. EClinicalMedicine 2020;23:100415.

Li L, Luengo-Fernandez R, Zuurbier Y, Beddows N, Lavallee P, Silver L, Kuker W, Rothwell P. Ten year risks of recurrent stroke, disability, dementia and cost in relation to site of primary intracerebral haemorrhage: population-based study. Journal of Neurology, Neurosurgery & Psychiatry 2020;91:580-585.

Bhatnagar R, Piotrowska HEG, Laskawiec-Szkonter M, Kahan BC, Luengo-Fernandez R, et al. Effect of thoracoscopic talc poudrage vs talc slurry via chest tube on pleurodesis failure rate among patients with malignant pleural effusions: a randomized clinical trial. JAMA 2020;323:60-69.

Luengo-Fernandez R, Violato M, Candio P, Leal J. Economic burden of stroke across Europe: a population-based cost analyses. European Stroke Journal 2020;5:17-25.

Bhatnagar R, Luengo-Fernandez R, Rahman NM, Miller RF, Maskell NA. Thoracoscopy and talc poudrage compared with intercostal drainage and talc slurry infusion to manage malignant pleural effusion: The TAPPS RCT. Health Technology Assessment 2020:24:1-90

Li L, Binney LE, Luengo-Fernandez R, Silver LE, Rothwell PM. Temporal trends in the accuracy of hospital diagnostic coding for identifying acute stroke: A population-based study. European Stroke Journal 2020;5:26-35.

Adams J, Barratt P, Arden NK, Barbosa Boucas S, Bradley S, Doherty M, Dutton S, Dziedzic K, Gooberman-Hill R, Hislop Lennie K, Hutt Greenyer C, Jansen V, Luengo-Fernandez R, Meagher C, White P, Williams M. The Osteoarthritis Thumb Therapyh (OTTER) II trial: a study protocol for a three-arm multi-centre randomised placebo controlled trial of the clinical effectiveness and efficacy and cost-effectiveness of splints for symptomatic base osteoarthritis. BMJ Open 9:e028342.

Luengo-Fernandez R, Penz E, Dobson M, Psallidas I, Nunn AJ, Maskell NA, Rahman NM. Cost effectiveness of intrapleural use of tissue plasminogen activator and DNase in pleural infection: Evidence from the MIST2 randomised controlled trial. European Respiratory Journal 2019; 54:doi: 10.1183/13993003.01550-2018

Kapoor M, Storrar W, Brown TP, Mansur A, Hedley E, Jones T, Roberts C, Shirkey B, Dutton S, Luengo-Fernandez R, Little M, Dewey A, Marshall S, Fogg C, Boughton K, Rahman N, Yu L, Bradding P, Howarth P, Chauhan AJ. Nocturnal temperature-controlled laminar airflow device for adults with severe allergic asthma: the LASER RCT. Health Technology Assessment 2019;23(29).

Leal J, Luengo-Fernandez R, Stratton IM, Dale A, Ivanova K, Scanlon PH. Cost-effectiveness of digital surveillance clinics with Optical Coherence Tomography versus hospital eye service follow up for patients with screen positive maculopathy. Eye 2019;33:640-647

Luengo-Fernandez R, Howard DPJ, Nichol KG, Dobell E, Rothwell PM. Hospital and institutionalisation care costs after limb and visceral ischaemia benchmarked against stroke: long-term results of a population-based cohort Study. Eur J Vasc Endovasc Surgery 2018;56:271-281

Ganesh A, Luengo-Fernandez R, Wharton RM, Rothwell PM. Ordinal vs. dichotomous analyses of modified Rankin Scale, 5-year outcome, and cost of stroke. Neurology 2018;91:e1951-e1960

Ganesh A, Luengo-Fernandez R, Pendlebury ST, Rothwell PM. Long-term consequences of worsened post-stroke status in patients with premorbid disability: implications for treatment. Stroke 2018;49:2430-2436.

Tsiachristas A, Waite A, Freeman D, Luengo-Fernandez R. Cost-effectiveness of cognitive-behavioural therapy for sleep disorder added to usual care in patients with schizophrenia: the BEST study. BJPsych Open 2018;4:126-135.

Ganesh A, Luengo-Fernandez R, Wharton RM, Gutnikov SA, Silver LE, Mehta Z, Rothwell PM. Time course of evolution of disability and cause-specific mortality after ischemic stroke: Implications for trial design. J Am Heart Assoc 2017;6:e005788.

Olfert JA, Penz ED, Manns BJ, Mishra EK, Davies HE, Miller RF, Luengo-Fernandez R, Gao S, Rahman NM. Cost-effectiveness of indwelling pleural catheter compared with talc in malignant pleural effusion. Respirology 2017;22:764-770.

Luengo-Fernandez R, Burns R, Leal J. Economic burden of non-malignant blood disorders across Europe: a population-based cost study. Lancet Haematol 2016;3:e371-e378.

Burns R, Leal J, Sullivan R, Luengo-Fernandez R. Economic burden of malignant blood disorders across Europe: a population-based cost study. Lancet Haematol 2016;3:e362-e370.

Morris S, Patel NV, Dobson J, Featherstone RL, Richards T, Luengo-Fernandez R, Rothwell PM, Brown MM. Cost-utility analysis of stenting versus endarterectomy in the International Carotid Stenting Study. Int J Stroke 2016;11:446-453.

Leal J, Luengo-Fernandez R, Sullivan R, Witjes JA. Economic burden of bladder cancer across the European Union. Eur Urol 2016;69:438-447.

Storrar W, Fogg C, Brown T, Dennison P, Yu LM, Dewey A, Luengo-Fernandez R, Dean T, Rahman N, Mansur A et al. Temperature-controlled laminar airflow in severe asthma for exacerbation reduction (the LASER trial): study protocol for a randomised controlled trial. Trials 2016;17:15.

Luengo-Fernandez R, Leal J, Gray A. UK research spend in 2008 and 2012: comparing stroke, cancer, coronary heart disease and dementia. BMJ Open 2015;5:e006648.

Freeman D, Waite F, Startup H, Myers E, Lister R, McInerney J, Harvey AG, Geddes J, Zaiwalla Z, Luengo-Fernandez R et al. Efficacy of cognitive behavioural therapy for sleep improvement in patients with persistent delusions and hallucinations (BEST): a prospective, assessor-blind, randomised controlled pilot trial. Lancet Psych 2015;2:975-983.

Scanlon PH, Aldington SJ, Leal J, Luengo-Fernandez R, Oke J, Sivaprasad S, Gazis A, Stratton IM. Development of a cost-effectiveness model for optimisation of the screening interval in diabetic retinopathy screening. Health Technol Assess 2015;19:1-116.

Yiin GS, Howard DPJ, Paul NL, Luengo-Fernandez R, Bull LM, Welch SJ, Gutnikov SA, Mehta Z, Rothwell PM. Circulation 2014;130:1236-1244.

Luengo-Fernandez R, Leal J, Gray AM, Sullivan R. The economic burden of cancer across the European Union: a population-based cost analysis. Lancet Oncol 2013;14:1165-1174.

Luengo-Fernandez R, Gray AM, Bull LM, Welch SJV, Cuthbertson F, Rothwell PM, for the Oxford Vascular Study. Quality of life after TIA and stroke: 10-year results of the Oxford Vascular Study. Neurology 2013;81:1588-1595.

Luengo-Fernandez R, Paul N, Gray AM, Pendlebury ST, Bull LM, Welch SJV, Cuthbertson F, Rothwell PM, and on behalf of the Oxford Vascular Study. A population-based study of disability and institutionalisation after TIA and stroke: 10-year results of the Oxford Vascular Study. Stroke 2013;44:2854-2861.

Freeman D, Startup H, Myers E, Harvey A, Geddes J, Yu L-Y, Zaiwalla Z, Luengo-Fernandez R, Foster R, Lister R. Effects of using cognitive behavioural therapy to improve sleep for patients with delusions and hallucinations (The BEST study): study protocol for a randomised controlled trial. Trials 2013;14:214.

Luengo-Fernandez R, Silver L, Gutnikov S, Gray A, Rothwell P. Hospitalisation resource use and costs before and after TIA and stroke: Results from a population-based cohort study (OXVASC). Value in Health 2013;16:280-287.

Paul NLM, Koton S, Simoni S, Geraghty OC, Luengo-Fernandez R, Rothwell PM. Feasibility, safety and cost of outpatient management of acute minor ischaemic stroke: a population-based study. J Neurol Neurosurg Psychiatry 2013;84:356-361.

Luengo-Fernandez R, Yiin G, Gray AM, Rothwell PM. Population-based study of acute- and long-term care costs after stroke in patients with AF. Int J Stroke 2013;8:308-314.

Luengo-Fernandez R, Gray AM, Rothwell PM, and on behalf of the Oxford Vascular Study. A Population-Based Study of Hospital Care Costs During 5 Years After Transient Ischemic Attack and Stroke. Stroke 2012;43:3343-3351.

Luengo-Fernandez R, Leal J, Gray A. UK research expenditure on dementia, heart disease, stroke and cancer: Are levels of spending related to disease burden? Eur J Neurol 2012;19:149-154

Luengo-Fernandez R, Leal J, Gray A. Cost of Dementia in the Pre-Enlargement Countries of the European Union. J Alzheimers Dis 2011;27:187-196.

Luengo-Fernandez R, Hernandez-Quesada C, Rivero-Arias O. Economic evaluation of healthcare technologies: an introduction for physicians. Rev Neurol 2011;53:107-115.

Chandratheva A, Geraghty OC, Luengo-Fernandez R, Rothwell PM. ABCD2 Score Predicts Severity Rather Than Risk of Early Recurrent Events After Transient Ischemic Attack. Stroke 2010;41:851-856.

Koton S, Luengo-Fernandez R, Mehta Z, Rothwell PM. Independent Validation of the Prolonged Length of Stay Score. Neuroepidemiology 2010;35:263-266.

Rivero-Arias O, Ouellet M, Gray A, Wolstenholme J, Rothwell PM, Luengo-Fernandez R. Mapping the Modified Rankin Scale (mRS) measurement into the generic EuroQol (EQ-5D) health outcome. Med Decis Making 2010;30:341-354.

Luengo-Fernandez R, Gray AM, Rothwell PM. Effect of urgent treatment for transient ischaemic attack and minor stroke on disability and hospital costs (EXPRESS study): a prospective population-based sequential comparison. Lancet Neurol 2009;8:235-243

Luengo-Fernandez R, Gray AM, Rothwell PM. Costs of stroke using patient-level data: a critical review of the literature. Stroke 2009;40:e18-e23.

Leal J, Luengo-Fernandez R, Gray A, Petersen S, Rayner M. Economic burden of cardiovascular diseases in the enlarged European Union. Eur Heart J 2006;27:1610-1619.

Luengo-Fernandez R, Gray AM, Rothwell PM. Population-based study of determinants of initial secondary care costs of acute stroke in the United Kingdom. Stroke 2006;37:2579-2587.

Luengo-Fernandez R, Leal J, Gray A, Petersen S, Rayner M. Cost of cardiovascular diseases in the United Kingdom. Heart 2006;92:1384-9.

McIntosh E, Luengo-Fernandez R. Economic evaluation. Part 1: Introduction to the concepts of economic evaluation in health care. J Fam Plann Reprod Health Care 2006;32:107-112.

McIntosh E, Luengo-Fernandez R. Economic evaluation. Part 2: frameworks for combining costs and benefits in health care. J Fam Plann Reprod Health Care 2006;32:176-180.