PRU-MHC: Policy Research Unit in Maternal Health & Care (2010 - 2018)

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Introduction

The Policy Research Unit in Maternal Health and Care (PRU-MHC) was established in 2010 with funding from the Department. Health. The Unit is based in the National Perinatal Epidemiology Unit, University of Oxford. The aim of the PRU-MHC is to conduct research and review existing evidence to improve the care given to women, their babies and their families by contributing to the evidence base for clinical practice and health-policy at the national and local level. The Unit has four research themes with a series of projects being conducted under each theme over the five year period of the PRU-MHC funding. The PRU-MHC researchers also undertake additional projects responding to policy information requests from the DH; these can be short or long term projects.

Details

Key researchers based in the PRU-MHC

Contact details

Name
Prof Jenny Kurinczuk
Organisation
Policy Research Unit in Maternal Health & Care (PRU-MHC)
Address
National Perinatal Epidemiology Unit (NPEU)
Nuffield Department of Population Health
University of Oxford
Old Road Campus

Oxford
OX3 7LF
Email
jenny.kurinczuk@npeu.ox.ac.uk
Telephone
01865 289719
Fax
01865 289701

1. The healthy mother and child (15 projects)

Factors associated with breastfeeding: analysis of area-based data and a women's survey

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First time mothers' expectations and experiences of postnatal care in England

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Informing policy on childbirth choices: the Birthplace Choices project

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National Maternity Survey 2014; women's experience of maternity care

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Peer Support for Women: Evaluation of models of peer support for women through pregnancy and the transition to parenthood

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Social patterning of smoking during pregnancy - evaluating the need for targeted interventions.

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The role of fathers in the development of the healthy child using ALSPAC

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The role of fathers in the development of the healthy child using the MCS

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UK TOBY Cooling Register: register of the use of moderate hypothermia in neonates

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What makes children resilient? Investigating the mechanisms of resilience in children whose mothers were postnatally depressed

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2. Pregnancy loss and perinatal mortality (4 projects)

Enhancing the Safety of Midwifery-Led Births Enquiry (ESMiE): A confidential enquiry of term, intrapartum-related perinatal deaths in births planned in midwifery-led settings in England & WAles

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Ethnic variations in birth outcomes and infant mortality in England and wales, 2006-2012

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Listening to parents: women's experience of care in the context of pregnancy loss and neonatal death

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3. Maternal morbidity and mortality (7 projects)

Factors associated with progression from near-miss maternal morbidity to fatality

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Impact of maternal age on intrapartum interventions and outcomes: secondary analysis of the Birthplace in England national prospective cohort study

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Impact of maternal BMI on intrapartum outcomes: secondary analysis of the Birthplace national prospective cohort study

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Long-term follow-up of women and their infants affected by near-miss morbidity

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4. Perinatal mental health and disabilities' (3 projects)

Improving outcomes for pregnant women with disability and their families

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The frequency with which women are currently asked about their emotional and mental health

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* (141 projects)

4Child - Analysis of 15 year trends and causes of vision loss in children

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4Child - Monitoring rates of cerebral palsy, particularly in high risk subgroups

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A population-based national study of the surgical outcomes of infants born with anorectal malformations.

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A population-based national study of the surgical outcomes of infants born with duodenal atresia.

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A population-based national study of the surgical outcomes of infants born with posterior urethral valves.

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A population-based study of the effect of infertility and its treatment on child health and development

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A population-based study of the health and developmental consequences of preterm birth

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ADEPT trial - early versus delayed enteral feeding for babies born with absent or reversed end-diastolic flow and growth restriction

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Association between infertility treatment and perinatal outcomes and infant health and development in a national UK survey

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Baby-OSCAR - Outcome after Selective Early Treatment for Closure of Patent Ductus ARteriosus in Pre-term Babies

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BAPS-CASS - A population-based national study of surgical outcomes of infants born with gastroschisis

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BAPS-CASS - A population-based national study of surgical outcomes of infants born with oesophageal atresia

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BAPS-CASS: A population-based national study of the surgical outcomes of infants born with Hirschsprung's disease

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BAPS-CASS: Surveillance of the surgical outcomes of infants with Meconium Ileus

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BAPS-CASS: Surveillance of the surgical outcomes of infants with necrotising enterocolitis

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Before, during and after birth - how does care affect the future health prospects of infants with congenital diaphragmatic hernia? (UKOSS study)

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Birthplace follow-on analysis to enhance policy and service delivery decision-making for planned place of birth

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BOOST-II UK trial - targeting oxygen saturation levels in preterm babies

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Breastfeeding and hospitalisation for infection in the 2010 Infant Feeding Survey

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CAROBB - Monitoring rates of congenital anomalies for surveillance purposes and research

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Clinical and/or cost-effectiveness of first trimester ultrasound screening for fetal anomalies: Is a prospective study an efficient investment?

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Comparison of different sources of incidence data for amniotic fluid embolism

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CORONIS (International study of caesarean section surgical techniques : the follow-up study)

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CORONIS Trial - a fractional factorial unmasked randomised controlled trial of caesarean section surgical techniques in developing countries

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E-Freeze - Freezing of embryos in assisted conception: a randomised controlled trial evaluating the clinical and cost-effectiveness of a policy of freezing embryos followed by thawed frozen embryo transfer, compared with a policy of fresh embryo transfer

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Economic evaluation of different second-line therapies for peripartum haemorrhage

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Educational outcomes in a population-based cohort of infants born with gastroschisis

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Effect of social deprivation on gestational age and size at birth

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Effects of prenatal alcohol consumption and alcohol metabolising genes on child growth and neurodevelopment in the ALSPAC study

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ELFIN trial - a multi-centre randomised placebo-controlled trial of prophylactic enteral lactoferrin supplementation to prevent late-onset invasive infection in very preterm infants

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ePrime - Evaluation of MR imaging to predict neurodevelopmental impairment in preterm infants

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EUPHRATES trial - trial of blood collector bag in third stage of labour

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EUROCAT - European Surveillance of Congenital Anomalies - Survey of prenatal diagnosis screening methods across Europe Perinatal screening for birth defects in Europe - a EUROCAT study of the impact of different national policies

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Evidence to improve the quality and safety of midwifery-led intrapartum care

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Examining the impact of introducing ICD-MM on observed trends in maternal mortality rates in the UK 2003-13

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I2S2 - Iodine supplementation trial - iodine supplementation for premature babies

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Immersion in water for pain relief and the risk of intrapartum transfer among low risk nulliparous women: secondary analysis of the Birthplace national prospective cohort study

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Incidence, risk factors and management of epidural haematoma and abscess

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Incidence, risk factors and outcomes of maternal sepsis in a Scottish region over 23 years

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Inequalities in Infant Mortality work programme - barriers to the early initiation of antenatal care by BME women

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Investigating differences in the incidence of near-miss maternal morbidity between women from different age, socioeconomic and ethnic groups

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Investigation of the completeness of case ascertainment by UKOSS using FMAIT as one of the candidate conditions

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Investigation of the completeness of case ascertainment by UKOSS using gastroschisis as one of the candidate conditions

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Maternal and Neonatal Outcomes of Antenatal Anaemia in a Scottish Population: a retrospective cohort study.

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Minidex: The efficacy and safety of very low dose dexamethasone used to facilitate the extubation of ventilator dependent preterm babies who are at high risk of bronchopulmonary dysplasia

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National Maternal, Newborn and Infant Clinical Outcome Review Programme

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National Maternity Survey 2010: women's experience of maternity care

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National survey of women's views and experience of maternity care 2006

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Neonatal unit survey of communication, facilities and support for parents of preterm babies

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NEST trial - Whole body cooling for neonates undergoing extracorporeal membrane oxygenation (ECMO)

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Nurse staffing in relation to risk adjusted mortality in neonatal care

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Obesity and outcome of pregnancy. Surveillance of extreme obesity in pregnancy Title: An international comparative study examining extreme maternal obesity

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Offer and uptake of antenatal screening for Downs syndrome in women from different social and ethnic backgrounds

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Optimising neonatal service provision for preterm babies born between 27 and 31 weeks gestation in England using national data, qualitative research and economic analysis

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PITCHES: Phase III trial in IntrahepaTic CHolestasis of pregnancy (ICP) to evaluate urSodeoxycholic acid (UDCA) in improving perinatal outcomes

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Poppi - a single centre randomised placebo-controlled trial investigating the efficacy of morphine analgesia for procedural pain in infants

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Pre-eclampsia in Hospital: Early Induction or Expectant management (PHOENIX).

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Progression from severe sepsis in pregnancy to death: a UK population-based case-control analysis

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Relationship between family income and child asthma: an econometric perspective

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Review of methods for neurodevelopmental follow-up of preterm infants after two years of age

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Risk factors and infant outcomes associated with maternal deaths in the UK from 2009-13: a national case control study

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Screening for iron deficiency and iron deficiency anaemia in pregnancy: a structured review and gap analysis against UK national screening criteria.

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Severe obstetric morbidity amongst women from different socioeconomic groups in Victoria

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Surveillance and case control study of antenatal pulmonary embolism

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Surveillance of aortic dissection/dissecting aortic aneurysm in pregnancy

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Surveillance of different methods of treating obstetric haemorrhage

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Surveillance of massive transfusion in major obstetric haemorrhage

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Surveillance of pregnancy in women following non-renal solid organ transplant

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Surveillance of Severe Primary Immune Thrombocytopenia (ITP) in pregnancy

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Systematic review of the use of the EPDS in screening for postnatal depression

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The association between maternal anaemia and pregnancy outcomes: a cohort study in Assam, India.

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The experience of women whose babies are admitted to a neonatal unit

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The impact of family income on child cognitive and behavioural outcomes in the United Kingdom

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The Oxford Worries about Labour Scale: maternal concerns about labour and birth

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TOBY Children Study - School age outcomes following a newborn cooling trial

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TOBY Trial - whole body cooling for babies born with neonatal encephalopathy

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TOBY Xenon: Neuroprotective effects of hypothermia combined with inhaled xenon following perinatal asphyxia

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Transfer from midwifery unit to obstetric unit during labour: rates, process, outcomes and women's experience

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UKCP Collaboration: Analysis of survival and regional variations in CP rates

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UKCP Collaboration: regional variations in the relationship between cerebral palsy and socio-economic deprivation

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Using record linkage to enhance and validate data collected in the Millennium Cohort Study

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Validation of a perceptions of care adjective check list for labour and birth

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Working with hospitals to maximise the benefits of studies of near-miss maternal morbidity

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