Kathryn Bunch

Kathryn Bunch

Profile

Epidemiologist

Kathryn joined NPEU in 2014 and is currently working on a review of modifiable risk factors for stillbirths and also the analysis of some of the UKOSS datasets.

Email: kathryn.bunch@npeu.ox.ac.uk

Biography

After completing a maths degree, Kathryn Bunch worked briefly for the Test Development and Research Unit of the Oxford and Cambridge exam boards before joining the Agricultural and Food Research Council's Institute for Research on Animal Diseases at Compton in Berkshire and then in 1989 she moved to the Childhood Cancer Research Unit in Oxford. During 25 years at CCRG, Kathryn worked on a variety of epidemiological studies including assessments of childhood cancer risk arising from both ionising and non-ionising radiation exposure and the role of paternal occupational exposure for different diagnostic subgroups. Other studies have investigated cancer risk in children born following assisted conception, the relationship between birthweight and childhood cancer risk and adverse effects among childhood cancer survivors. Following the closure of the CCRG in 2014, Kathryn joined NPEU where she has been working on a still birth review and undertaken analysis of some of the UKOSS datasets as well as assisting with further analysis of the birthplace study data for the recent National Maternity Services Review.  

Publications

Kendall GM, Wakeford R, Bunch KJ, Vincent TJ and Little MP (2015). Residential mobility and associated factors in relation to the assessment of exposure to naturally occurring radiation in studies of childhood cancer.  Journal of Radiological Protection 35(4):835-868

Bunch KJ, Swanson J, Vincent TJ and Murphy MFG (2015). Magnetic fields and childhood cancer: An epidemiological investigation of the effects of high-voltage underground cables. Journal of Radiological Protection 35(3):695-705. 

Swanson J, Bunch KJ, Vincent TJ and Murphy MFG (2015). Reply to 'Comment on: Childhood cancer and exposure to corona ions from power lines: an epidemiological study'. Journal of Radiological Protection 35 (2015): 485–486

O'Neill KA, Murphy FGM, Bunch KJ, Puumala SE, Carozza SE, Chow EJ, Mueller BA , McLaughlin CC, Reynolds P, Vincent TJ, Behren J and Spector LG (2015). Infant birthweight and risk of childhood cancer: International population-based case control studies of 40 000 cases.  International Journal of Epidemiology 44(1):153-168

McNally RJQ, Bunch KJ, Craft AW and Murphy MFG (2014) Response to: Comment on 'Updated investigations of cancer excesses in individuals born or resident in the vicinity of Sellafield and Dounreay'.  British Journal of Cancer 112: 1837

Swanson J, Bunch KJ, Vincent TJ and Murphy, MFG (2014). Childhood cancer and exposure to corona ions from power lines: An epidemiological test. Journal of Radiological Protection 34(4): 873-888

Swanson J, Vincent TJ and Bunch KJ (2014) Relative accuracy of grid references derived from postcode and address in UK epidemiological studies of overhead power lines. Journal of Radiological Protection 34(4): N81-N86

Bunch KJ, Tim Vincent TJ, Black RJ, Pearce MS, McNally RJ, McKinney PA, Parker L, Craft AW, and Murphy MFG (2014) Updated investigations of cancer excesses in individuals born or resident in the vicinity of Sellafield and Dounreay  Br J Cancer 111: 1814-1823

Bunch, K. J., T. Keegan, J. Swanson, T. J. Vincent and M. F. G. Murphy (2014). "Residential distance at birth from overhead high-voltage powerlines: childhood cancer risk in Britain 1962-2008." Br J Cancer. 110: 1402-1408

Williams CL, Bunch KJ, Stiller CA, Murphy MFG, Botting BJ, Wallace H, Davies M, Sutcliffe AG(2013) Cancer risk among children born after assisted conception. N Engl J Med 369 (19): 1819-1827

Neale, R. E., Stiller, C. A., Bunch, K. J., Mineau, G., and Murphy, M. F. G. (2013) Parental cancer and childhood/young adult cancer in the Utah Genealogy. Int J Cancer 133(12): 2953-2960.

Keegan TJ, Bunch KJ, Vincent TJ, King JC, O'Neill KA, Kendall GM, MacCarthy A, Fear NT, Murphy MF (2013) Case-control study of paternal occupation and social class with risk of childhood central nervous system tumours in Great Britain, 1962-2006. Br J Cancer 108 (9): 1907-1914

Kendall GM, Little MP, Wakeford R, Bunch KJ, Miles JCH, Vincent TJ, Meara JR, Murphy MFG (2013) A record-based case-control study of natural background radiation and the incidence of childhood leukaemia and other cancers in Great Britain during 1980-2006. Leukemia 27 (1): 3-9

Kendall, G. M., Bunch, K. J., Miles, J. C. H. M., Vincent, T. J., Little, M. P., Wakeford, R., Meara, J. R., and Murphy, M. F. G. Report of a record-based case-control study of natural background radiation and incidence of childhood cancer in Great Britain. HPA-CRCE-045. 2013. Chilton,Didcot, Health Protection Agency.

MacCarthy A, Bayne AM, Brownbill PA, Bunch KJ, Diggens NL, Draper GJ, Hawkins MM, Jenkinson HC, Kingston JE, Stiller CA, Vincent TJ, Murphy MF (2013) Second and subsequent tumours among 1927 retinoblastoma patients diagnosed in Britain 1951-2004. Br J Cancer 108 (12): 2455-2463
 

Keegan TJ, Bunch KJ, Vincent TJ, King JC, O'Neill KA, Kendall GM, MacCarthy A, Fear NT, Murphy MFG (2012) Case-control study of paternal occupation and risk of childhood leukaemia in Great Britain, 1962-2006. Br J Cancer 107 (9): 1652-1659

O'Neill KA, Bunch KJ, Murphy MFG (2012) Intrauterine growth and childhood leukemia and lymphoma risk. Expert Rev Hematol  5 (5): 559-576

O'Neill KA, Bunch KJ, Vincent TJ, Spector LG, Moorman AV, Murphy MFG (2012) Immunophenotype and cytogenetic characteristics in the relationship between birth weight and childhood leukemia. Pediatr Blood Cancer 58 (1): 7-11

Kendall, G. M. and Bunch, K. J. Cancer in the offspring of radiation workers, RAD August 2011. RAD Magazine 37, 15-16. 2011.
 

MacCarthy A, Bunch KJ, Fear NT, King JC, Vincent TJ, Murphy MFG (2010) Paternal occupation and neuroblastoma: a case-control study based on cancer registry data for Great Britain 1962-1999. Br J Cancer 102 (3): 615-619

Bunch KJ, Muirhead CR, Draper GJ, Hunter N, Kendall GM, O'Hagan JA, Phillipson MA, Vincent TJ, Zhang W (2009) Cancer in the offspring of female radiation workers: a record linkage study. Br J Cancer 100 (1): 213-218

Fear NT, Vincent TJ, King JC, MacCarthy A, Bunch KJ, Murphy MFG (2009) Wilms Tumour and Paternal Occupation: An Analysis of Data From the National Registry of Childhood Tumours. Pediatr Blood Cancer 53 (1): 28-32

Levitt G, Anazodo A, Burch M, Bunch K (2009) Cardiac or cardiopulmonary transplantation in childhood cancer survivors: an increasing need? Eur J Cancer 45 (17): 3027-3034

MacCarthy A, Bunch KJ, Fear NT, King JC, Vincent TJ, Murphy MFG (2009) Paternal occupation and retinoblastoma:  A case-control study based on data for Great Britain 1962-1999. Occup Environ Med 66 (10): 644-649

Muirhead, C. R., Bunch, K. J., Hunter, N., Draper, G. J., Kendall, G. M., O'Hagan, J. A., Phillipson, M. A., Vincent, T. J., and Zhang, W. Cancer in the Offspring of Female Radiation Workers - a Record Linkage Study. HPA-RPD-063. 2009. Chilton,Didcot, Health Protection Agency.
 

Murphy MFG, Bunch KJ, Chen B, Hemminki K (2008) Reduced occurrence of childhood cancer in twins compared to singletons: protection but by what mechanism? Pediatr Blood Cancer 51 (1): 62-65

Stiller C (2007) Childhood cancer in Britain: incidence, survival, mortality. Oxford University Press: Oxford (Contributed Chapter 6 on Childhood Cancer Mortality)

Lightfoot T, Bunch K, Ansell P, Murphy M (2005) Ovulation induction, assisted conception and childhood cancer. Eur J Cancer 41 (5): 715-724

Kroll ME, Passmore SJ, Stiller CA, Draper GJ, Bayne AM, Brownbill PA, Bunch KJ, Vincent TJ, Murphy MFG (2004) Childhood Cancer - UK. In CancerStats Monograph 2004, Toms JR (ed) pp 63-72. Cancer Research UK:

Sorahan T, Haylock RGE, Muirhead CR, Bunch KJ, Kinlen LJ, Little MP, Draper GJ, Kendall GM, Lancashire RJ, English MA (2003) Cancer in the offspring of radiation workers: an investigation of employment timing and a reanalysis using updated dose information. Br J Cancer 89 (7): 1215-1220

Dockerty JD, Draper GJ, Vincent TJ, Rowan SD, Bunch KJ (2001) Case-control study of parental age, parity and socioeconomic level in relation to childhood cancers. Int J Epidemiol 30 (6): 1428-1437

Murphy MFG, Whiteman D, Hey K, Griffith M, Gill L, Goldacre MJ, Vincent TJ, Bunch KJ (2001) Childhood cancer incidence in a cohort of twin babies. Br J Cancer 84 (11): 1460-1462

Stiller CA, Bunch KJ, Lewis IJ (2000) Ethnic group and survival from childhood cancer:  report from the UK Children's Cancer Study Group. Br J Cancer 82 (7): 1339-1343

Doyle P, Bunch KJ, Beral V, Draper GJ (1998) Cancer incidence in children conceived with assisted reproduction technology. Lancet 352 (9126): 452-453

Draper GJ, Little MP, Sorahan T, Kinlen LJ, Bunch KJ, Conquest AJ, Kendall GM, Kneale GW, Lancashire RJ, Muirhead CR, O'Connor CM, Vincent TJ (1997) Cancer in the offspring of radiation workers: a record linkage study. BMJ 315 (7117): 1181-1188

Draper GJ, Little MP, Sorahan T, Kinlen LJ, Bunch KJ, Conquest AJ, Kendall GM, Kneale GW, Lancashire RJ, Muirhead CR, O'Connor CM, Vincent TJ, Thomas JM, Goodill AA, Vokes J, Haylock RGE (1997) Cancer in the Offspring of Radiation Workers - a Record Linkage Study. NRPB: Didcot

Levitt G, Bunch KJ, Rogers CA, Whitehead B (1996) Cardiac transplantation in childhood cancer survivors in Great Britain. Eur J Cancer 32A (5): 826-830

Black RJ, Urquhart JD, Kendrick SW, Bunch KJ, Warner J, Adams Jones D (1992) Incidence of leukaemia and other cancers in birth and schools cohorts in the Dounreay area. BMJ 304  (6839): 1401-1405

Stiller CA, Bunch KJ (1992) Brain and spinal tumours in children aged under two years: incidence and survival in Britain, 1971-85.  Br J Cancer 66 (Suppl. XVIII): S50-S53

Stiller CA, McKinney PA, Bunch KJ, Bailey CC, Lewis IJ (1991) Childhood cancer and ethnic group in Britain: a United Kingdom Children's Cancer Study Group (UKCCSG) study. Br J Cancer 64 (3): 543-548

Stiller CA, Bunch KJ (1990) Trends in survival for childhood cancer in Britain diagnosed 1971-85. Br J Cancer 62 (5): 806-815

Hall GA, Parsons KR, Waxler GL, Bunch KJ, Batt RM (1989) Effects of dietary change and          rotavirus infection on small intestinal structure and function in gnotobiotic piglets. Research in veterinary science 47(2): 219-24

Baggott DG, Bunch KJ, Gill KR (1988) Variations in some inorganic components and physical properties of claw keratin associated with claw disease in the British Friesian cow. The British veterinary journal 144(6): 534-42

Craven N, Williams MR, Field TR, Bunch KJ, Mayer SJ, Bourne FJ (1986) The influence of extracellular and phagolysosomal pH changes on the bactericidal activity of bovine neutrophils against Staphylococcus aureus. Veterinary immunology and immunopathology 13(1-2): 97-110

Reynolds DJ, Morgan JH, Chanter N, Jones PW, Bridger JC, Debney TG, Bunch KJ (1986) Microbiology of calf diarrhoea in southern Britain. The Veterinary record 119(2): 34-9

Rowlands GJ, Bunch KJ, Brookes PA, Manston R (1986) Relationship between the blood composition of Friesian (Holstein) bulls and their improved contemporary comparisons for production traits. The Journal of Agricultural Science 107(01): 71-74

Field TR, Williams MR, Bunch KJ (1985) An improved method for the isolation of a neutrophil-rich fraction from porcine blood. The British veterinary journal 141(4): 355-61

Williams MR, Craven N, Field TR, Bunch KJ (1985) The relationship between phagocytosis and intracellular killing of Staphylococcus aureus by bovine neutrophils. The British veterinary journal 141(4): 362-71

Williams MR, Hibbitt KG, Field TR, Bunch KJ (1984) Further studies on the variation among cows, bulls and calves in the ability of their blood polymorphonuclear leucocytes to kill Staphylococcus aureus. The British veterinary journal 140(3): 307-13

Bunch KJ, Heneghan DJS, Hibbitt KG, Rowlands GJ (1984) Genetic influences on clinical mastitis and its relationship with milk yield, season and stage of lactation. Livestock Production Science 11(1): 91-104

Hall GA, Parsons KR, Batt RM, Bunch KJ (1983) Quantitation of small intestinal structure and function in unthrifty piglets. Research in veterinary science 34(2): 167-72

Rowlands GJ, Manston R, Bunch KJ, Brookes PA (1983) A genetic analysis of the concentrations of blood metabolites and their relationships with age and liveweight gain in young British Friesian bulls. Livestock Production Science 10(1): 1-16

Sansom BF, Bunch KJ, Dew SM (1982) Changes in plasma calcium, magnesium, phosphorus and hydroxyproline concentrations in ewes from twelve weeks before until three weeks after lambing. The British veterinary journal 138(5): 393-401

Matthews PR, Collins P, Bunch KJ, McDiarmid A (1982) The virulence of Mycobacterium avium and related mycobacteria for C57 mice. Journal of comparative pathology 92(3): 387-92

Williams MR, Bunch KJ (1981) Variation among cows in the ability of their blood polymorphonuclear leucocytes to kill Escherichia coli and Staphylococcus aureus. Research in veterinary science 30(3): 298-302

Hibbitt K, Hill AW, Williams MR, Bunch KJ (1980) Factors affecting the resistance of the mammary gland to infection and the influence of the sire on the susceptibility of his daughters to mastitis. Proc of the International Conference on Resistant Factors and Genetic Aspects of Mastits Control