Ed Juszczak

Associate Professor Ed Juszczak BSc(Hons), MSc, CStat CSci


Associate Professor - Director, NPEU Clinical Trials Unit

Ed Juszczak has over 20 years of experience working in medical statistics, and since 1998 has specialised in clinical trial design, conduct, analysis and interpretation, publishing in the highest impact journals.

Email: ed.juszczak@npeu.ox.ac.uk


Ed Juszczak graduated in Applied Statistics from Sheffield City Polytechnic in 1992, and obtained a Masters degree (MSc) in Medical Statistics from the London School of Hygiene & Tropical Medicine a year later. He then spent 5 years in the Information & Statistics Division of the NHS in Scotland developing an expertise in the design and analysis of case control and cohort studies. In 1998 he joined the Centre for Statistics in Medicine, and as Senior Medical Statistician headed a small dedicated team of statisticians supporting clinical research, predominantly randomised controlled trials (RCTs) and teaching medical statistics to non-statisticians.

Subsequently Ed joined the National Perinatal Epidemiology Unit in September 2007 as Head of Trials, where he oversees a Clinical Trials Unit running a portfolio of typically around 18 neonatal and maternal clinical trials at various stages of completion. He has considerable experience in the design, conduct, analysis and reporting of RCTs, with a particular interest in multi-arm trials and the use of statistics in the areas of neonatology, paediatrics, mental health and surgery. Ed sits on several data monitoring and trial steering committees and in 2007 was conferred the title 'University Research Lectureship' by the University of Oxford, followed in 2010 by the award of Chartered Scientist (CSci) by the Science Council.

More recently, Ed has become the representative for Clinical Trials Units on the National Institute for Health Research Medicines for Children Research Network Neonatal Clinical Study Group, an executive member of the National Reproductive Health Research Network Clinical Study Group in Fetal Medicine and a Steering Group member of the UKCRC network registered CTU Statisticians Working Group.

In April 2013, Ed was designated Director of the NPEU CTU, and in the summer of 2013, Ed joined the NIHR HTA Commissioning Board. More recently, in October 2014, Ed was awarded the title of Associate Professor, and in November 2016, he joined the newly established NIHR HTA General Board.

For news about the latest research aimed at protecting newborn babies from Necrotising Enterocolitis (a life-threatening bowel problem), funded by Action Medical Research and led by Ed and collaborators from the University of Southampton click here.


1. Azzopardi D, Strohm B, Edwards AD, Halliday H, Juszczak E, Levene M, Thoresen M, Whitelaw A, Brocklehurst P. Treatment of asphyxiated newborns with moderate hypothermia in routine clinical practice: how cooling is managed in the UK outside a clinical trial. Arch Dis Child Fetal Neonatal Ed. 2009;94(4):F260-F64. doi: 10.1136/adc.2008.146977.

2. Azzopardi DV, Strohm B, Edwards AD, Dyet L, Halliday HL, Juszczak E, Kapellou O, Levene M, Marlow N, Porter E, Thoresen M, Whitelaw A, Brocklehurst P. Moderate Hypothermia to Treat Perinatal Asphyxial Encephalopathy. N Engl J Med. 2009;361(14):1349-58. doi: 10.1056/NEJMoa0900854.

3. Edwards AD, Brocklehurst P, Gunn AJ, Halliday H, Juszczak E, Levene M, Strohm B, Thoresen M, Whitelaw A, Azzopardi D. Neurological outcomes at 18 months of age after moderate hypothermia for perinatal hypoxic ischaemic encephalopathy: synthesis and meta-analysis of trial data. Br Med J. 2010;340:c363. doi: 10.1136/bmj.c363.

4. Field D, Firmin R, Azzopardi D, Cowan F, Juszczak E, Brocklehurst P, the NEST Study Group. Neonatal ECMO Study of Temperature (NEST) - a randomised controlled trial. BMC Pediatr. 2010;10(1):24. doi: 10.1186/1471-2431-10-24.

5. Zhang W-H, Deneux-Tharaux C, Brocklehurst P, Juszczak E, Joslin M, Alexander S. Effect of a collector bag for measurement of postpartum blood loss after vaginal delivery: cluster randomised trial in 13 European countries. Br Med J. 2010;340:c293. doi: 10.1136/bmj.c293.

6. CAESAR study collaborative group. Caesarean section surgical techniques: a randomised factorial trial (CAESAR). BJOG. 2010;117(11):1366-76. doi: 10.1111/j.1471-0528.2010.02686.x.

7. Johnston ED, Boyle B, Juszczak E, King A, Brocklehurst P, Stenson BJ. Oxygen targeting in preterm infants using the Masimo SET Radical pulse oximeter. Arch Dis Child Fetal Neonatal Ed. 2011;96(6):F429-F33. doi: 10.1136/adc.2010.206011.

8. Juszczak E, Farrell B. The CORONIS Trial: international study of caesarean section surgical techniques. Trials. 2011;12(Suppl 1):A103.

9. Morgan K, Juszczak E, Bowler U. A practical solution to 'Continuing Care site' issues in neonatal clinical trials - a pragmatic approach to regulatory and research governance review. Trials. 2011;12(Supp 1):A37. doi: 10.1186/1745-6215-12-S1-A37.

10. The INIS Collaborative Group, Brocklehurst P, Farrell B, King A, Juszczak E, Darlow B, Haque K, Salt A, Stenson B, Tarnow-Mordi W. Treatment of Neonatal Sepsis with Intravenous Immune Globulin. N Engl J Med. 2011;365(13):1201-11. doi: 10.1056/NEJMoa1100441.

11. Azzopardi D, Strohm B, Linsell L, Hobson A, Juszczak E, Kurinczuk JJ, Brocklehurst P, Edwards AD, on behalf of the UKTCR. Implementation and Conduct of Therapeutic Hypothermia for Perinatal Asphyxial Encephalopathy in the UK – Analysis of National Data. PLoS One. 2012;7(6):e38504. doi: 10.1371/journal.pone.0038504.

12. Leaf A, Dorling J, Kempley S, McCormick K, Mannix P, Linsell L, Juszczak E, Brocklehurst P. Early or Delayed Enteral Feeding for Preterm Growth-Restricted Infants: A Randomized Trial. Pediatrics. 2012;129(5):e1260-8. doi: 10.1542/peds.2011-2379.

13. Barber V, Linsell L, Locock L, Powell L, Shakeshaft C, Lean K, Colman J, Juszczak E, Brocklehurst P. Electronic fetal monitoring during labour and anxiety levels in women taking part in a RCT. British Journal of Midwifery. 2013;21(6):394-403.

14. BOOST II United Kingdom Collaborative Group, BOOST II Australia Collaborative Group, BOOST II New Zealand Collaborative Group, Stenson BJ, Tarnow-Mordi WO, Darlow BA, Simes J, Juszczak E, Askie L, Battin M, Bowler U, Broadbent R, Cairns P, Davis PG, Deshpande S, Donoghoe M, Doyle L, Fleck BW, Ghadge A, Hague W, Halliday HL, Hewson M, King A, Kirby A, Marlow N, Meyer M, Morley C, Simmer K, Tin W, Wardle SP, Brocklehurst P. Oxygen Saturation and Outcomes in Preterm Infants. N Engl J Med. 2013;368(22):2094-104. doi: 10.1056/NEJMoa1302298.

15. The CORONIS Collaborative Group, Ablos E, Addo V, Brocklehurst P, El Sheikh M, Farrell B, Gray S, Hardy P, Juszczak E, Mathews JE, Masood SN, Oyarzun E, Oyieke J, Sharma JB, Spark P. Caesarean section surgical techniques (CORONIS): a fractional, factorial, unmasked, randomised controlled trial. The Lancet. 2013;382(9888):234-48. doi: 10.1016/S0140-6736(13)60441-9.

16. The SIFT Investigators Group. Early enteral feeding strategies for very preterm infants: current evidence from Cochrane reviews. Arch Dis Child Fetal Neonatal Ed. 2013;98(6):F470-2. doi: 10.1136/archdischild-2012-303260.

17. Field D; NEST Study Collaborative Group. Neonatal ECMO Study of Temperature (NEST): A Randomized Controlled Trial. Pediatrics. 2013;132(5):e1247-56. doi: 10.1542/peds.2013-1754.

18. CORONIS Collaborative Group, Abalos E, Oyarzun E, Addo V, Sharma JB, Matthews J, Oyieke J, Masood SN, El Sheikh MA, Brocklehurst P, Farrell B, Gray S, Hardy P, Jamieson N, Juszczak E, Spark P. CORONIS - International study of caesarean section surgical techniques: the follow-up study. BMC Pregnancy Childbirth. 2013;13:215. doi: 10.1186/1471-2393-13-215.

19. Kempley S, Gupta N, Linsell L, Dorling J, McCormick K, Mannix P, Juszczak E, Brocklehurst P, Leaf A, ADEPT Trial Collaborative Group. Feeding infants below 29 weeks' gestation with abnormal antenatal Doppler: analysis from a randomised trial. . Arch dis Child Neonatal Ed. 2014;99(1):F6-F11. doi: 10.1136/archdischild-2013-304393.

20. Williams F, Hume R, Ogston S, Brocklehurst P, Morgan K, Juszczak E. A Summary of the Iodine Supplementation Study Protocol (I2S2): A UK Multicentre Randomised Controlled Trial in Preterm Infants. Neonatology. 2014;105(4):282-289.