Charles Opondo BPharm MSc PhD

Researcher in Statistics and Epidemiology


Charles attended the University of Nairobi in Kenya and graduated with a degree in Pharmacy in 2005. Thereafter he worked as a Pharmacist in the Ministry of Health and gained his pharmacist's professional registration.

He then joined the KEMRI-University of Oxford-Wellcome Trust Collaborative Research Programme in Nairobi in 2007 initially as an intern (later becoming a research assistant and research officer) to work in a cluster randomised trial testing interventions to improve the quality of care for children admitted to Kenyan district hospitals.

He was awarded a Wellcome Trust Masters Fellowship in 2009 to study Medical Statistics at the London School of Hygiene and Tropical Medicine. At the end of these studies in 2010 he went back to Nairobi to continue with his research. He returned to the LSHTM in 2011 to work towards a PhD in Medical Statistics which he was awarded at the end of 2014.

Charles joined the NPEU in January 2015 as a Researcher in Statistics and Epidemiology. He is currently working with the Policy Research Unit in Maternal Health and Care on a project looking at the impact of fathers on child development, and a project exploring the role of social deprivation in explaining variations in health outcomes in infants.

His other research is at the London School of Hygiene and Tropical Medicine where he's involved in the design and analysis of a portfolio of trials in the Medical Statistics Department's Clinical Trials Unit.


Bonell C, Allen E, Opondo C, Warren E, Elbourne DR, Sturgess J, Bevilacqua L, McGowan J, Mathiot J, Viner RM (February 2019) Examining intervention mechanisms of action using mediation analysis within a randomised trial of a whole-school health intervention. JECH

Ward A, Guillot A, Nepomnyashchiy LE, Graces JC, Maloney K, Omoniwa OF, Emegbuonye L, Opondo C, Kerac M, Omuolabi E, Bhattacharya A, Hariharan KM, Wiwa O, Cohen JM, Le Menach A (January 2019) Seasonal malaria chemoprevention packaged with malnutrition prevention in northern Nigeria: A pragmatic trial (SMAMP study) with nested case-control. PLoS One 14(1):1-20.

Fellmeth G, Rose-Clarke K, Zhao C, Busert L, Zheng Y, Massazza A, Sonmez H, eder B, Blewitt A, Lertgrai W, Orcutt M, Ricci K, Mohamed-Ahmed O, Burns R, Knipe D, Hargreaves S, Hesketh T, Opondo C, Devakumar D. (December 2018) Health impacts of parental migration on left-behind children and adolescents: a systematic review and meta-analysis. Lancet 392(10164):2567-2582.

Bonell C, Allen E, Warren E, McGowan J, Bevilacqua L, Jamal F, Legood R, Wiggins M, Opondo C, Mathiot A, Sturgess J, Fletcher A, Sadique Z, Elbourne D, Christie D, Bond L, Scott S, Viner R. (December 2018) Effects of the Learning Together intervention on bullying and aggression in English secondary schools (INCLUSIVE): a cluster randomised controlled trial. Lancet 392(10163): 2452-2464.

Hanson C, Betrán AP, Opondo C, Mkumbo E, Manzi F, Mbaruku G, Schellenberg J. (November 2018) Trends in Caesarean section rates between 2007 and 2013 in obstetric risk groups inspired by the Robson classification: Results from population based surveys in a low resource setting. Br J Obstet Gynaecol.

Bailey J, Lelijveld N, Marron B, Onyoo P, Ho LS, Manary M, Briend A, Opondo C, Kerac M (April 2018) Combined protocol for acute malnutrition study (ComPAS) in rural South Sudan and urban Kenya: study protocol for a randomised controlled trial. Trials 19:251.

Opondo C, Allen E, Todd J, English M. (February 2018) Association of the Paediatric Admission Quality of Care score with mortality in Kenyan hospitals: a validation study. Lancet Global Health 6(2):e203-e210.

Allen SM, Opondo C, Campbell OMR. (October 2017) Measuring facility capability to provide routine and emergency childbirth care to mothers and newborns: An appeal to adjust for delivery caseload of facilities. PLoS One 12(10): e0186515.

Opondo C, Redshaw M, Quigley MA. (June 2017) Association between father involvement and attitudes in early child-rearing and depressive symptoms in the pre-adolescent period in a UK birth cohort. Journal of Affective Disorders 221:115-122.

Fantaguzzi C, Allen E, Miners A, Christie D, Opondo C, Sadique Z, Fletcher A, Grieve R, Bonell C, Viner R, Legood R. (May 2017) Health-related quality of life associated with bullying and aggression: a cross-sectional study in English secondary schools. European Journal of Health Economics 1–11.

Walker NF, Wilkinson KA, Meintjes G, Tezera LB, Goliath R, Peyper JM, Tadokera R, Opondo C, Coussens AK, Wilkinson RJ, Friedland JS, Elkington PT (May 2017). Matrix Degradation in Human Immunodeficiency Virus Type 1–Associated Tuberculosis and Tuberculosis Immune Reconstitution Inflammatory Syndrome: A Prospective Observational Study. Clinical Infectious Diseases 86:913–22.

Opondo C, Redshaw M, Savage-McGlynn E, Quigley M (November 2016) Father involvement in early child-rearing and behavioural outcomes in their pre-adolescent children: evidence from the ALSPAC UK birth cohort. BMJ Open 6:e012034

Opondo C, Allen E, Todd J, English M (October 2016) The Paediatric Admission Quality of Care (PAQC) score: designing a tool to measure the quality of early inpatient paediatric care in a low-income setting. Tropical Medicine and International Health 21(10):1334–1345.

Lelijveld N, Seal A, Wells J, Kirby J, Opondo C, Chimwezi E, Bunn J, Bandsma R, Heyderman R, Nyirenda M, Kerac M (September 2016) Chronic disease outcomes after severe acute malnutrition in Malawian children (ChroSAM): a cohort study. Lancet Global Health 4(9): e654–e662.

Muinga N, Ayieko P, Opondo C, Ntoburi S, Todd J, Allen E, English M (June 2014) Using health worker opinions to assess changes in structural components of quality of care in a cluster randomised trial. BMC Health Services Research 28:282.

English M, Gathara D, Mwinga S, Ayieko P, Opondo C, Aluvaala J, Kihuba E, Mwaniki P, Were F, Irimu G, Wasunna A, Mogoa W, Nyamai R (January 2014) Adoption of recommended practices and basic technologies in a low-income setting. Archives of Disease in Childhood 0:1-5

Opondo C, Ayieko P, Ntoburi S, Wagai J, Opiyo N, Irimu G, Allen E, Carpenter J, English M (November 2011) Effect of a multi-faceted quality improvement intervention on inappropriate antibiotic use in children with non-bloody diarrhoea admitted to district hospitals in Kenya. BMC Paediatrics 11:109.

Gathara D, Opiyo N, Wagai J, Ntoburi S, Ayieko P, Opondo C, Wamae A, Migiro S, Mogoa W, Wasunna A, Were F, Irimu G, English M (November 2011) Quality of hospital care for sick newborns and severely malnourished children in Kenya: a two-year descriptive study in 8 hospitals. BMC Health Services Research 11:307.

Ayieko P, Ntoburi S, Wagai J, Opondo C, Opiyo N, Migiro S, Wamae A, Mogoa W, Were F, Wasunna A, Fegan G, Irimu G, English M (April 2011) A multifaceted intervention to implement guidelines and improve admission paediatric care in Kenyan district hospitals: a cluster randomized trial. Plos Medicine 8:e1001018.

Opondo C, Ntoburi S, Wagai J, Wafula J, Wasunna A, Were F, Wamae A, Migiro S, Irimu G, English M (October 2009) Are hospitals prepared to support newborn survival? – an evaluation of eight first-referral level hospitals in Kenya. Tropical Medicine and International Health 14: 1165–1172.

English M, Ntoburi S, Wagai J, Mbindyo P, Opiyo N, Ayieko P, Opondo C, Migiro S, Wamae A, Irimu G (July 2009) An intervention to improve paediatric and newborn care in Kenyan district hospitals: understanding the context. Implementation Science 4:42.