MaatHRI: Comparing the blood coagulation profile of pregnant women with and without anaemia

A cross-sectional study of coagulation parameters in 1200 pregnant women, 600 with haemoglobin <10g/dl (anaemia group) and 600 with haemoglobin ≥10g/dl (no-anaemia group).

The objectives are:

1. To estimate the difference in blood coagulation parameters between anaemia group and no-anaemia group during the third trimester of pregnancy.
2. To examine the relationship of blood coagulation parameters with haemoglobin and postpartum haemorrhage (PPH) in anaemic and non-anaemic pregnant women. 
3. To estimate the potentially adequate dose of tranexamic acid (TXA) for the treatment of PPH in pregnant women with moderate-severe anaemia.

Funding: This study is funded by the Nuffield Department of Population Health’s Pump-priming award.