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May tops recruitment

Great month of recruitment in May, with the highest month of consents and randomisations to date, with 33 couples randomised and 84 couples consented.

Cochrane review supports need for large randomised controlled trial

A new Cochrane review comparing fresh and frozen embryo transfer, supports the need for a large randomised controlled trial to understand the effectiveness of the two treatments.

The Cochrane review found that there was no significant difference in the cumulative live birth rate, however, the freeze all strategy was associated with lower OHSS (7% following conventional IVF/ICSI strategy versus between 1% and 3% for freeze-all) and a lower rate of miscarriage.

'UK first' IVF embryo trial

The NPEU Clinical Trials Unit is collaborating with the University of Aberdeen on a large-scale multi-centre trial comparing the use of ‘fresh’ and frozen embryos for IVF, the first of its kind in the UK. E-Freeze, funded by the NIHR Health Technology Assessment (HTA) Programme will recruit 1,086 couples to see which method produces the greatest number of healthy babies, as well as considering the health of the mother and costs to the health services and longer-term societal costs.  News about the trial has featured in The Scotsman and The Herald newspapers. Read more about E-Freeze.

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This study is funded by the National Institute for Health Research (NIHR) Health Technology Assessment (HTA) Programme (Reference Number 13/115/82). The views expressed are those of the author(s) and not necessarily those of the NIHR or the Department of Health and Social Care.